3种家用脱敏剂阻塞牙本质小管的实验研究  

Experimental study of three home application desensitizers for the occlusion of dentine tubules

作　　者：王盼盼[1] 陈新梅[2] 

机构地区：[1]口腔疾病研究国家重点实验室,四川大学 [2]四川大学华西口腔医院牙体牙髓病科,四川成都610041

出　　处：《国际口腔医学杂志》2010年第5期511-515,共5页International Journal of Stomatology

摘　　要：目的观察3种家用脱敏剂对牙本质小管的堵塞作用以比较它们的脱敏效果。方法制备敏感牙本质盘模型,分别采用不同的家用脱敏剂进行刷牙实验,以空白牙膏为对照。通过扫描电镜观察各组处理前后牙本质形态,电子能谱分析其表面元素变化,并采用图像分析软件处理扫描电镜图片,计算堵塞率。结果扫描电镜发现实验牙膏均能部分堵塞牙本质小管,但与对照组相比几种家用脱敏剂堵塞效果更加显著(P<0.05),堵塞方式各异,组间无统计学差异(P>0.05)。能谱分析证实堵塞物均含有F有效元素。结论 3种家用脱敏剂均能有效地堵塞牙本质小管,具有一定程度的脱敏作用。Objective The objective of this study was to evaluate the effects of three home application desensi-tizers（Sensodyne,Colgate and Xinxiaogan） on the occlusion of the dentinal tubules in vitro. Methods Dentin discs were used to prepare the dentin hypersensitivity model. Specimens were then subjected to brush experiment using different desensitizers with the common dentifrice serving as a control. Morphology of specimens in different groups before and after treatment were observed under scanning electron microscope（SEM）,meanwhile,active in-gredients on the dentine surface were analyzed by energy disperse spectroscopy（EDS）. The degree of occlusion of the dentinal tubules was quantified using an image analyser. Results Distinct surface coatings were observed by SEM in vertical and horizontal plane of dentin. The use of all desensitizers occluded tubules more than no brush-ing and brushing with ordinary dentifrice（P0.05）. There was no significant difference between all the experimental groups（P0.05）. In the clogging matter,EDS revealed the presence of active ingredients of F. Conclusion The tested dentifrices seem effective for desensitization by tubule occlusion.

关 键 词：脱敏剂 牙本质 牙本质敏感 

分 类 号：R781.2[医药卫生—口腔医学]