酮咯酸氨丁三醇注射液治疗急性胆绞痛的疗效观察  

Efficacy observation on Ketorolac tromethamine Injection in treatment patients with gallstone colic

作　　者：范小勇[1] 付明[1] 

机构地区：[1]河南省新乡市中心医院急诊科,河南新乡453000

出　　处：《中国医药导报》2010年第28期45-46,共2页China Medical Herald

摘　　要：目的:观察酮咯酸氨对胆绞痛患者的疗效及不良反应。方法:将180例患者随机分为3组,分别应用酮咯酸氨丁三醇(治疗组)、奈福泮(对照组1)和盐酸哌替啶(对照组2)进行肌内注射,观察比较三种药物的镇痛效果及不良反应。结果:酮咯酸氨丁三醇在镇痛效果与盐酸哌替啶比较,无显著性差异,但优于奈福泮。不良反应比较,酮咯酸氨丁三醇与奈福泮无显著性差异;两者与盐酸哌替啶比较,均有显著性差异,且副作用小。结论:酮咯酸氨丁三醇治疗急性胆绞痛时,镇痛疗效确切,不良反应少,值得临床推广。Objective： To observe efficacy and adverse reactions of Ketorolac tromethamine in treatment patients with gallstone colic. Methods： 180 patients were randomly divided into 3 groups, application of Ketorolac tromethamine （the treatment group）, Nefopam （control group 1） and Pethidine hydrochloride（control group 2） for intramuscular injection, observed and compared the three drugs in the analgesic effect and adverse reactions. Results： There was no difference between Ketorolac tromethamine and Pethidine hydrochloride hudrochloried in analgesic effect but excelling Nefopam. Comparison of adverse reactions, Ketorolac tromethamine was the same as Nefopam, but the two more significant with acceptable side ef fects compared with Pethidine hydrochloride. Conclusion： Ketorolac tromethamine is worth popularizing for its effective analgesia in treatment acute biliary gallstone colic , and less adverse reactions.

关 键 词：酮咯酸氨丁三醇 胆绞痛 奈福泮 盐酸哌替啶 

分 类 号：R575.6[医药卫生—消化系统]