中西医结合治疗对化疗后卵巢功能损害患者生活质量的影响  

The effect of conbined treatment of traditional Chinese medicine and western medicine on the quality of life in the patients of chemotherapy-induced premature ovarian failure

作　　者：秦佳佳[1,2] 李瑞满[1,3] 

机构地区：[1]暨南大学医学院,广东广州510632 [2]广州中医药大学博士后科研流动站 [3]暨南大学附属第一医院

出　　处：《中国妇幼保健》2010年第28期4145-4147,共3页Maternal and Child Health Care of China

基　　金：广州中医药大学创新基金(09cx036);广东省中医药局基金(A2007128)

摘　　要：目的:观察中西医结合治疗对化疗后卵巢功能损害患者生活质量的影响。方法:将2007～2009年暨南大学医学院53例化疗后导致卵巢功能损害患者随机分为治疗组(左归饮加减配合西药人工周期疗法)27例,对照组(西药人工周期疗法)26例,应用生存质量测定量表进行生存质量评定,观察治疗后两组生活质量及临床疗效变化。结果:①治疗组总有效率74.07%,对照组总有效率69.23%,差异有统计学意义。②治疗组生活质量各个维度均较治疗前明显提高(P<0.05,P<0.01);治疗后两组间比较,在生理功能维度、社会功能维度、情感职能维度3项中,治疗组较对照组明显改善(P<0.05)。结论:左归饮加减配合西药人工周期疗法可明显改善化疗后卵巢功能损害患者的生存质量。Objective：To observe the effect of conbined treatment of traditional Chinese medicine and western medicine on the quality of life in the patients of chemotherapy-induced premature ovarian failure.Methods：53 patients of chemotherapy-induced premature ovarian failure were divided into 2 groups randomly as treatment group （Zuoguiyin decoction and artificial cycle by western medicine,27 cases） and control group （only artificial cycle by western medicine,26 cases）.The quality of life was evaluated by Quality of Life Scale,and the changes of quality of life and clinical effects were observed after treatment in the 2 groups.Results：①The total effective rate was 74.07% in treatment group while 69.23% in control group.The difference was significant （P 0.05）.②Every index which could stand for the quality of life became better in treatment group after treatment （P 0.05,P 0.01）.The indexes of physiological function,social functions and role emotional in treatment group became better than control group after treatment （P 0.05）.Conclusion：Conbined treatment of traditional Chinese medicine and western medicine can ameliorate the quality of life in the patients of chemotherapy-induced premature ovarian failure.

关 键 词：卵巢功能损害 中西医结合治疗 生活质量 

分 类 号：R730.5[医药卫生—肿瘤]