Determination of N-nitrosodimethylamine in drinking water by UPLC-MS/MS  

作　　者：Wanfeng Wang Jianying Hu Jianwei Yu Min Yang 

机构地区：[1]. State Key Lab of Environmental Aquatic Chemistry, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China. [2]College of Environmental Science, Peking University, Beijing 100871, China

出　　处：《Journal of Environmental Sciences》2010年第10期1508-1512,共5页环境科学学报（英文版）

基　　金：supported by the National Special Funding Project for Water Pollution Control and Management of China(No.2009ZX07419-001,2008ZX07421-004);the Chinese Academy of Sciences Major Projects of Knowledge Innovation Program(No.kzcx-yw-06-02);the Special Co-construction Project of Beijing Municipal Commission of Education

摘　　要：The method for detecting N-nitrosodimethylamine （NDMA） in drinking water using ultra performance liquid chromatography （UPLC） coupled with tandem mass spectrometry （MS/MS） was improved by optimizing the clean-up procedure to remove the matrix interference in pretreatment process, and was then applied to a survey of NDMA in both raw and finished water samples from five water treatment plants in South China. The NDMA concentrations ranged from 4.7 to 15.1 ng/L in raw water samples, and from 4.68 to 46.9 ng/L in finished water. The NDMA concentration in raw water was found to be related with nitrite concentration, and during the treatment, the NDMA concentration increased following ozonation but decreased after subsequent activated carbon treatment.The method for detecting N-nitrosodimethylamine （NDMA） in drinking water using ultra performance liquid chromatography （UPLC） coupled with tandem mass spectrometry （MS/MS） was improved by optimizing the clean-up procedure to remove the matrix interference in pretreatment process, and was then applied to a survey of NDMA in both raw and finished water samples from five water treatment plants in South China. The NDMA concentrations ranged from 4.7 to 15.1 ng/L in raw water samples, and from 4.68 to 46.9 ng/L in finished water. The NDMA concentration in raw water was found to be related with nitrite concentration, and during the treatment, the NDMA concentration increased following ozonation but decreased after subsequent activated carbon treatment.

关 键 词：drinking water N-NITROSODIMETHYLAMINE UPLC-MS/MS the matrix interference 

分 类 号：TS264.4[轻工技术与工程—发酵工程] O658[轻工技术与工程—食品科学与工程]