电化学方法估算Au/硫醇/卵磷脂双层膜的表观有效厚度  

ASSESSING THE APPARENT EFFECTIVE THICKNESS OF THE SUPPORTED HYBRID BILAYER MEMBRANES BY ELECTROCHEMICAL METHODS

作　　者：崔晓丽[1,2] 蒋殿录[1,2] 李俊新[1,2] 刁鹏[1,2] 童汝亭[1,2] 王心葵[1,2] 

机构地区：[1]河北师范大学化学系 [2]中国科学院山西煤炭化学研究所

出　　处：《四川大学学报（自然科学版）》1999年第2期302-306,共5页Journal of Sichuan University(Natural Science Edition)

基　　金：河北省自然科学基金

摘　　要：以Ａｕ／硫醇／卵磷脂双层膜作为生物膜的模型体系，应用交流阻抗及循环伏安技术研究了该双层膜在不同浓度的Ｋ３Ｆｅ（ＣＮ）６／Ｋ４Ｆｅ（ＣＮ）６溶液中的电化学行为．结果表明，硫醇／卵磷脂双层膜没有明显的“针孔”缺陷，电子转移通过电子隧道实现．测得硫醇／卵磷脂双层膜电化学表观有效厚度为１６个ＣＨ２，低于硫醇分子及卵磷脂分子的链长总和。With the supported hybrid bilayer membrane consisting octadecanethiol and phospholipid as model of biological membrane,its electrochemical behaviors in different concentrations of Fe(CN) 3 /4 6 are investigated by electrochemical impedance spectroscopy and cyclic voltammetry technology.The electron transfer between gold and the redox species separated by the hybrid bilayer assembly is completed by electron tunneling process.It is also found that the apparent effective thickness of the hybrid bilayer is 16CH 2 that is lower than that of the sum of length of octadecanethiol and phospholipid,so some possible collapsed sites may be present in the hybrid bilayer membranes.

关 键 词：卵磷脂 双层膜 电化学法 生物膜 铕 硫醇 

分 类 号：Q734[生物学—分子生物学]