胃肠道外间质肿瘤七例临床病理分析  

Extrgastrointsetinal stromal tumor:a clinicopathologic analysis of 7 cases

作　　者：李正金[1] 田林波[1] 赵立仙[1] 李耀康[1] 毕磊[1] 

机构地区：[1]大理学院附属医院,云南大理671000

出　　处：《海南医学》2010年第19期88-89,共2页Hainan Medical Journal

摘　　要：目的探讨胃肠道外间质肿瘤的临床病理特征和诊断及鉴别诊断。方法分析7例胃肠道外间质肿瘤的临床病理特征并进行文献复习。结果 7例胃肠道外间质肿瘤中,1例位于前列腺,1例为腹膜后,5例为肠系膜。镜下6例为梭形细胞为主型,1例为上皮样细胞为主型。免疫组化示肿瘤细胞呈CD117+(6/7)、CD34+(7/7)、dog1+(7/7)、波形纤维蛋白(Vim+)(7/7),平滑肌肌纤蛋白(SMA)、S100蛋白、结蛋白(Des)均阴性。结论胃肠道外间质肿瘤是一种少见的肿瘤,需要与平滑肌瘤、平滑肌肉瘤、神经鞘瘤等鉴别,CD、dog和CD联合运用能提高诊断。Objective To study clinical pathologic characteristics,diagnosis and differential diagnosis of extrgastrointsetinal stromal tumor.Methods Clinical pathologic features were studied in EGIST with review of the literatures.Results In 7 cases of EGIST,the tumor were situated in prostate （1 case）,in mesenterium （5 cases）,in retroperitoneal（1 case）.The tumor were mainly composed of spindle cell （6/7） or epithlioid cell （1/7）.Immunohistochemically,CD117＋（6/7）,CD34＋（7/7）,dog1＋（7/7）and Vim＋（7/7）,SMA-,S100-and Des-.Conclusion EGIST is a rare tumor,Immunohistochemical makers（CD34、dog1 and CD117） are important for diagnosis and differential diagnosis.

关 键 词：间质肿瘤 胃肠道外 临床病理 诊断和鉴别 

分 类 号：R735[医药卫生—肿瘤]