9例成人型肺母细胞瘤的病理诊断与鉴别诊断  

Pathological and differential diagnosis for adult type pulmonary blastoma

作　　者：刘爱军[1] 李维华[1] 李静波 许红民[1] 陈乐真[1] 张杰 曾木英[1] 

机构地区：[1]中国人民解放军总医院病理科,100853 [2]齐齐哈尔市北满特钢职工医院 [3]石油管道局中心医院

出　　处：《诊断病理学杂志》1999年第2期75-77,共3页Chinese Journal of Diagnostic Pathology

摘　　要：目的探讨成人型肺母细胞瘤的临床病理学特点及鉴别诊断。方法收集9例成人型肺母细胞瘤，复习患者病历档案并进行组织学观察和随访。结果9例成人型肺母患者年龄为31～78岁，平均52岁。获访的8例患者7例病故于术后5～18个月，术后平均生存10．3个月。肿瘤位于肺门（中央型）者2例，位于周边肺膜下（周围型）者7例；组织学表现为双相型者8例：既有复杂的胚胎性腺管结构又有幼稚的始基成分和分化程度不等的梭形细胞。上皮型者1例：主要由复杂的分枝状腺管构成。部分腺上皮形态相似于子宫内膜样腺体。结论成人型肺母是一恶性度极高的肿瘤，高发年龄为50岁左右。诊断上应注意与肺的癌肉瘤、肺腺癌及儿童型肺母等鉴别。Objective To investigate the clinicopathologic features of adult type pulmonary blastoma (PB) and make differenteialdiagnosis from other pulmonary tumors . Methods Nine cases of adult type PB were analyzed by meas of reviewing the review of history records ,reading HE slides and follow-up. Results The age range of patients was from 31 to 78 years (mean 52 years). Seven cases were died of the disease in a period of 5 ~ 18 months after diagnosis . The average survival time was 10.3 months. Two cases were central in type, intra-and peribronchial type, and 7 cases were peripheral type. Histologically, eight cases of nine were biphasic type, and only one case was epithelial type. Conclusion The adult type PB is a malignancy with very poor prognosis, and should be distinguished from children type PB, pulmonary adenocrcinoma and carcinosarcoma .

关 键 词：母细胞瘤 成人型 病理诊断 鉴别诊断 肺肿瘤 

分 类 号：R734.204[医药卫生—肿瘤] R730.43[医药卫生—临床医学]