多系统萎缩64例临床特点分析  

Clinical analysis of 64 cases with multiple system atrophy

作　　者：林兴建[1] 尹俊雄[1] 刘卫国[1] 

机构地区：[1]南京医科大学附属南京脑科医院神经内科,江苏南京210029

出　　处：《中国医药导报》2010年第29期131-133,共3页China Medical Herald

摘　　要：目的:探讨多系统萎缩的发病特点,临床表现,预后等,为临床诊断提供依据。方法:回顾性分析64例多系统萎缩的首发症状、临床特点、头颅MRI以及诱发电位等,结合文献进行复习。结果:64例患者包括橄榄桥脑小脑变性(MSA-C型)39例,纹状体黑质变性(MSA-P型)15例和Shy-Drager综合征(MSA-A型)10例,三种分型虽然早期表现不同,但却是同一疾病过程的不同阶段。头颅影像学以及诱发电位异常阳性率高。结论:随着各种检查手段的改进,尤其是神经影像学、神经电生理等的不断发展,对本病的诊断水平明显提高。Objective： To analyze initiate characteristics, clinical characteristics and prognosis of multiple system atrophy （MSA） in order to offer more evidence for the correct diagnosis of this disease. Methods： Retrospectively analyzed 64 cases MSA including the beginning symptom, clinical characteristic, brain MRI and evoked potentials, combine with recently literature to refresh. Results： 64 cases patients including MSA-C 39 cases, MSA-P 15 cases and MSA-A 10 cases. Although these three types had different symptoms in the beginning, they were just one disease on different phase. The rate of brain MRI and evoked potentials abnormal was highly. Conclusion： With the developing of various kinds examine methods, especially NeuroImage and electrophysiology methods, obviously enhance the diagnosis of MSA.

关 键 词：多系统萎缩 橄榄桥脑小脑变性(MSA-C型) 纹状体黑质变性(MSA-P型) Shy-Drager综合征(MSA-A型) 头颅MRI 诱发电位 

分 类 号：R742[医药卫生—神经病学与精神病学]