趋化因子CXC亚家族及其与肿瘤的生物学关系  

CXC chemokine subfamily and its biological relationship with tumor

作　　者：朱庆超[1] 汪昱[1] 

机构地区：[1]上海交通大学附属第六人民医院普外科,上海200233

出　　处：《国际外科学杂志》2010年第10期693-697,共5页International Journal of Surgery

摘　　要：趋化因子是一类具有化学趋化功能的多肽，CXC类趋化因子是趋化因子大家族中的一个亚族；在肿瘤细胞的发生、发展中常伴随着一系列的分子生物学改变，趋化因子CXC亚家族与机体对肿瘤的免疫应答及其与生物学之间有着密切的关系。本文就趋化因子CXC亚族中的几个成员及其受体与肿瘤的生物学关系进行综述。Chemokines are a class of functional chemotactic peptide. CXC chemokine class is a large family of chemokines in a sub- tribe. In the occurrence and development of tumor cells, there often accompa- nied by a series of molecular and biology change. CXC chemokine subfamily is closely related to the body＇ s immune response to tumor and biological behaviors of tumor. In this paper, CXC chemokine sub-Several members of the tribe and their receptor and tumor biological relationship are reviewed.

关 键 词：趋化因子 CXCL 受体 肿瘤 

分 类 号：R730.2[医药卫生—肿瘤]