老年人认知功能障碍特点和经颅多普勒检查的关系研究  

Study of relationship between cognitive impairment and TCD in elderly patients

作　　者：卞光荣[1] 肖辉[1] 李乐军[1] 邵凤扬[1] 蒋娟[1] 

机构地区：[1]江苏省连云港市中医院,222004

出　　处：《山西医药杂志（上半月）》2010年第10期922-923,共2页Shanxi Medical Journal

基　　金：江苏省连云港市卫生局基金(ZC248)

摘　　要：目的研究老年人认知功能障碍(CI)特点和经颅多普勒检查(TCD)的关系。方法使用简易智能状态(MMSE)量表评定智能,对59例老年人CI组和38例认知功能正常组(对照组)患者进行TCD脑血流速度检查。结果老年人CI表现在定向、即刻记忆、注意和计算、回忆、言语表达、图形描述能力减退明显,而物体命名、语言复述、阅读理解能力下降不明显;CI组颈内动脉系统及总的血流异常血管数目明显多于对照组;定向、即刻记忆、注意和计算、回忆、言语表达、图形描述评分与颈内动脉系统血流异常血管数目呈负相关。结论老年CI患者的智能损害尽管广泛,但并非是全面均一的损害,认知功能多项指标与TCD颈内动脉系统脑血流异常血管数目有相关性。Objective To investigate the relationship between cognitive impairment and TCD in elderly patients. Methods The mini mental state （MMSE） scale was used to assess intelligence,CI （cognitive impairment,CI） group and control group （normal cognitive function） with TCD examination. Results CI performance of the elderly in the orientation,immediate memory,attention and calculation,memory,verbal expression,graphical representation of ability decline significantly,while no significant decline was observed in the object naming,rehearsal,and reading comprehension; the number of abnormal blood vessels is more than in the total carotid blood flow of CI group control group; orientation,immediate memory,attention and calculation,memory,verbal expression,graphical representation of score and carotid artery blood flow was negatively correlated with the number of abnormal blood velocity.Conclusion Despite of the widespread intellectual impairment,the damage is not fully homogeneous in CI elderly patients. There is correlation between cognitive dysfunction and cerebral blood flow velocity.

关 键 词：认知障碍 老年人 血流速度 

分 类 号：R749.1[医药卫生—神经病学与精神病学]