高度近视RNFL厚度在诊断原发性开角型青光眼中的临床意义  被引量:5

The clinical value of measuring RNFL in diagnosis of primary open-angle glaucoma with high myopia

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作  者:张敏芳[1] 孟晓红[1] 冉黎[1] 李莎[1] 

机构地区:[1]第三军医大学西南眼科医院,重庆市400038

出  处:《中国实用眼科杂志》2010年第9期969-971,共3页Chinese Journal of Practical Ophthalmology

摘  要:目的评估光学相干断层成像术(Optical Coherence Tomography,OCT)定量测量视网膜神经纤维层厚度(Retinal Nerve FiberLayer,RNFL)在诊断高度近视合并原发性开角型青光跟(primaryopen—angle glaucoma,POAG)中的临床意义。方法收集高度近视患者(屈光度≥-6.00D)其40例73只眼,分为单纯高度近视组(A组)及高度近视合并POAG组(B组),所有的患者均行眼压、前房角镜、全自动视野及OCT检查。结果(1)A组患者平均眼压(16.57±2.43)mmHg,视野检查平均敏感度(MS)23.63±3.70;OCT检查RNFL平均厚度(单位μm)分别为上象限:117.64±15.78,下象限:126.05±22.55,鼻象限:95.694±4.99,颞象限:100.1±27.25;(2)B组患者平均眼压为(26.45±6.02)mmHg,视野检查平均敏感度(MS)15.41±7.63;OCT检查RNFL平均厚度(单位μm)分别为上象限:99.38±36.39,下象限:95.10±33.85,鼻象限:68.00±17.56,颞象限:70.62±25.57。(3)分别对两组RNFL各象限厚度值进行t检验,结果显示两组间差异显著均有统计学意义(P〈0.01)结论正确评估高度近视RNFL的定量测量在原发性开角型青光服早期诊断中具有重要意义。Objective To evaluate the clinical value of measuring retinal nerve fiber layer (RNFL) thickness using optical coherence tomography (OCT) in diagnosis of primary open-angle glaucoma (POAG) with high myopia. Methods We collected 73 eyes of 40 cases diagnosed with high myopia (diopter ≥6. 00D). They were divided into simple high myopia (group A) and high myopia with POAG (group B). All pa- tients underwent intra-ocular tension, goniscope examination, visual field and OCT. Results In group A, average intraocular pressure (IOP): 16.57± 2.43 (mmHg); visual field examination: mean sensitivity: 23.63± 3.70; the mean RNFL thickness around optical nerve head were in the superior: 117.64± 15.78 (μ m), inferior: 126.05± 22.55 (μ m), nasal: 95.69± 34.99 (μ m), temporal: 100.1±27.25 (μ m), respectively. In group B, av- erage lOP: 26.45± 6.02 (mmHg); visual field examination: mean sensitivity: 15.41± 7.63; the mean RNFL thickness around optical nerve head were in the superior: 99.38:1:36.39 (μ m), inferior: 95.10± 33.85 (μm), nasal: 68.00± 17.56 (μm), temporal: 70.62± 25.57 (μ m), respectively. Independent-Samples T Test was applied for RNFL thickness comparisons of different quadrants between two groups. The results showed there was significant difference between two groups (P 〈0.01). Conclusions It has significant clinical meaning to exactly evaluate the application value of measuring retinal nerve fiber layer in POAG with high myopia

关 键 词:高度近视 原发性开角型青光眼 视网膜神经纤维层厚度 

分 类 号:R775.2[医药卫生—眼科]

 

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