5例胃肝样腺癌临床病理分析  

Clinicopathological Study of HAS

作　　者：侍孝红[1] 王前玉 陈焰[2] 朱季军 

机构地区：[1]南京鼓楼医院集团宿迁市人民医院病理科,江苏宿迁223800 [2]南京鼓楼医院集团宿迁市人民医院普外科,江苏宿迁223800 [3]南京鼓楼医院集团宿迁市人民医院消化科,江苏宿迁223800

出　　处：《现代肿瘤医学》2010年第10期2012-2014,共3页Journal of Modern Oncology

摘　　要：目的:探讨胃肝样腺癌(HAS)病理学形态、免疫组化和临床特征。方法:对5例手术切除的肝样腺癌做临床病理学研究和免疫组织化学检查。结果:HAS多见于老年男性,肿块多位于胃窦,由肝样腺癌伴或不伴普通腺癌组成,肝样腺癌病理形态与原发性肝细胞癌形态相同。肿瘤易转移,预后差。免疫组织化学AFP、α1-AT、α1-ACT阳性。结论:胃肝样腺癌是原发于胃黏膜的癌,组织形态与肝细胞癌相似,常有血清AFP升高,术后监测血清AFP可以提示肿瘤复发或转移,预后较普通胃腺癌差。Objective：To evaluate the pathomorphology,immunohistochemical and clinical characters of HAS.Methods：Clinicopathological and immunohistochemical studies were performed on 5 HAS patients.Results：HAS often lied in gastric antrum and caught by older man.The morphosis of the heptodifferentiation zone was similar to that of the carcinoma of liver.HAS widely infiltrated the artery and vein.The prognosis are often poor.Immunohistochemically,the cancer cells were positive for AFP,ATT,ACT.Conclusion：HAS is gastric carcinoma,the morphosis of the heptodifferentiation zone was similar to that of the carcinoma of liver,and often showed a significant high level of serum AFP.The detection of serum AFP postoperatively may be helpful in predicting recurrence or metastasis for carcinoma.The prognosis is poor.

关 键 词：胃 肝样腺癌 免疫组织化学 

分 类 号：R735.2[医药卫生—肿瘤]