得保松和甲氨蝶呤联合注射治疗婴幼儿血管瘤67例  

Local Injection of Diprospan with Methotrexate(MTX) in the management of infantile hemangioma

作　　者：廖洪跃 欧阳天祥[2] 黄大江 周军 李影 吴礼诚 邹来兴 

机构地区：[1]武警江西省总队医院整形外科,江西南昌3300030 [2]上海交通大学附属新华医院整形外科,上海200092

出　　处：《中国美容医学》2010年第9期1352-1354,共3页Chinese Journal of Aesthetic Medicine

摘　　要：目的:探讨治疗婴幼儿血管瘤有效和创伤小的方法。方法:婴幼儿血管瘤患者67例,年龄2～15月,头面部42例,颈部6例,躯干16例,四肢3例;增生期58例,消退期9例;所有病例使用瘤体间质内注射得保松与甲氨蝶呤混合液。结果:所有病例均经过0.5～2年的随访,治愈26例,基本治愈33例,好转7例,无效1例。结论:得保松联合甲氨蝶呤局部注射疗法适合于大多数血管瘤的治疗,能够控制血管瘤的生长,促进其消退,而且治疗容易,创伤小,无明显副作用。Objective To study the therapy of infantile hemangiomas with effectively and minimally invasive. Methods A total of 67 patients with hemangiomas were treated by the same surgeon from September,the study ranging in age from 2 months to 15 months,among the 67 patients,42 hemangiomas were located on the head and face,6 on the neck,16 on the trunk,and 3 on the extremities.According to Mulliken biological cataloge,58 hemangiomas in growth stage and 9 in involution stage. Apply the injection of Diprospan with MTX in interstitial tissue of the hemangioma. Results All patients were followed up for a half year to 2 years.Follow up results showed that 26 patients were cured,33 were greatly improved,7 were partly improved,and 1 patient was noobvious improvement. Conclusions Local injection of Diprospan with MTX is suitable to for the treatment of most infantile hemangiomas,which can well control the growth of the lesion and improve to involute.1t＇s a easy,minimally jnvasive approach to treat hemangiomas and also provides an barely effect.

关 键 词：血管瘤 婴幼儿 得保松 甲氨蝶呤 

分 类 号：R732.2[医药卫生—肿瘤]