基于散斑跟踪技术的实时心肌声学造影图像定量分析  

Quantitative Analysis of Real-time Myocardial Contrast Echocardiography Based on Speckle Tracking Technique

作　　者：李新彩[1] 孙丰荣[1] 张明强[2] 贾晓波[1] 姚桂华[3] 张运[3] 

机构地区：[1]山东大学信息科学与工程学院,山东济南250100 [2]曲阜师范大学物理工程学院,山东曲阜273165 [3]山东大学齐鲁医院心内科,山东济南250012

出　　处：《航天医学与医学工程》2010年第5期351-355,共5页Space Medicine & Medical Engineering

基　　金：国家自然科学基金项目(61071053);山东省优秀中青年科学家科研奖励基金项目(2005BS1006);山东大学自主创新基金项目(2009TS106)

摘　　要：目的解决实时心肌声学造影图像定量分析中心肌感兴趣区域(ROI)的帧间失准问题。方法采用Brox的多分辨率光流场计算方法对RT-MCE序列图像进行散斑跟踪,使得ROI区域的位置在每一帧上都精确标记同一个心肌区域,再进行定量分析。结果实现了心肌ROI位置的实时自动校准,定量分析曲线符合临床描述。结论多分辨率光流散斑跟踪技术能解决心肌ROI的帧间失准问题,并能在临床MCE图像定量分析中得到应用。Objective To solve the interest frame misalignment in myocardial region for the quantitative analysis of real-time myocardial contrast echocardiography. Methods RT-MCE sequences were tracked with Brox＇ s multi-discriminative rate algorithm of optical flow field technique and every frame of the same myocardial area was marked exactly with the position of region of interest （ROI）. Then quantitative analysis was conducted. Results Real-time and automatic calibration of the myocardial ROI was realized and the curves of the experi- ments were consistent with clinical description. Conclusion The proposed method can solve the frame mis- alignment problem and can be employed in clinical quantitative analysis on RT-MCE.

关 键 词：光流场 散斑跟踪 多分辨率 实时心肌声学造影 

分 类 号：R318[医药卫生—生物医学工程] R445.1[医药卫生—基础医学]