短暂性脑缺血发作患者多种凝血相关指标的变化  

Serum levels of some coagulant indexes in transient ischemic attacks patients

作　　者：陈蓓蕾[1] 李晓波[1] 袁成林[1] 

机构地区：[1]苏北人民医院神经科,江苏扬州225009

出　　处：《中风与神经疾病杂志》2010年第9期834-836,共3页Journal of Apoplexy and Nervous Diseases

基　　金：江苏省科技支撑计划(BE2009653)

摘　　要：目的研究短暂性脑缺血发作患者vWF,FⅧ:C及各种凝血相关指标的变化极其临床意义。方法检测并分析70例短暂性脑缺血发作患者及70例健康人血液vWF,FⅧ:C,FIB,ATⅢ,PT,APTT,TT和PT-INR水平。结果与健康对照组相比短暂性脑缺血发作患者的vWF和FⅧ:C水平较高。且vWF和FⅧ:C水平较高者更易进展为脑梗死。短暂性脑缺血发作患者与健康对照组的FIB,ATⅢ,PT,APTT,TT和PT-INR水平无明显差异。结论短暂性脑缺血发作患者凝血系统激活。检测血液vWF,FⅧ:C水平将有助于我们诊断和治疗短暂性脑缺血发作。Objective To study serum levels and their clinical significance of vWF,FVIII：C and some other coagulant indexes in TIA patients.Methods The serum levels of vWF,FⅧ：C,FIB,ATⅢ,PT,APTT,TT and PT-INR were respectively detected in TIA group consisting of 70 patients and control group consisting of 70 health persons.Results Compared with the control,the serum levels of vWF and FVIII：C were higher in TIAs,and we found that the higher the levels were,the more likely to evolve to infarction.Whereas,there were no significant differences of FIB,ATIII,PT,APTT,TT and PT-INR between the two groups.Conclusion Coagulation process is activated in TIAs.Testing the serum levels of vWF and FⅧ：C helps to diagnose and treat TIAs.

关 键 词：短暂性脑缺血发作 凝血 血管性假性血友病因子 凝血因子Ⅷ:C 

分 类 号：R743.31[医药卫生—神经病学与精神病学]