岛叶及其深部结构非对称性的MRI研究  

Asymmetry of the insula and its deep structures:an MRI study

作　　者：宋永瑞[1,2,3] 王震寰[1,4] 季公俊[1,4] 隋东莉[1,4] 李成[1,4] 

机构地区：[1]蚌埠医学院临床应用解剖研究所人体解剖学教研室,安徽蚌埠233030 [2]蚌埠医学院 [3]蚌埠医学院第一附属医院放射科,安徽蚌埠233004 [4]蚌埠医学院组织移植安徽省重点实验室,安徽蚌埠233030

出　　处：《蚌埠医学院学报》2010年第10期979-981,985,共4页Journal of Bengbu Medical College

基　　金：安徽省跨世纪学术和技术带头人后备人选科研资助项目(2002HBL26)

摘　　要：目的:研究左、右侧大脑半球岛叶及其深部结构的非对称性。方法:在微型计算机上使用e-film工作站,选取30名正常人头颅横断面MRI图像的岛叶层面,将图像导入Adobe Photoshop 10.0软件中进行测量,得出岛叶区域左、右两侧95%可信区间典型层面距正中矢状面距离,经统计学分析得出各层两侧距离差异。结果:岛叶中央沟、前环岛沟、下环岛沟各层面距正中矢状面距离均数以左侧大于右侧为主,占88%;其中岛叶中央沟区段(Z=-3～15 mm层面)、前环岛沟近脑底部层面(Z=0～-9 mm层面)、下环岛沟中下部区段(Z=-9～9mm层面)距离左侧大于右侧,距离均数差异均有统计学意义(P<0.05～P<0.01);其余各典型层面两侧距离差异均无统计学意义(P>0.05)。结论:岛叶及其深部结构区总体形态上,在岛叶中央沟区、前环岛沟近脑底部层面、下环岛沟中下部层面区域呈现出明显左侧大于右侧的趋势,此区域各结构的功能是否存在非对称性,及结构非对称性是否与大脑半球其他局部区域的结构与功能非对称性相关,尚待进一步研究。Objective：To investigate the structural asymmetry of the insula and its deep structure between the left and right hemispheres.Methods：Using e-film workstation based on computer,cross-section MRI scan images of the brain among thirty cases of healthy population were chosen,images which involve the insula were impoted into photoshop 10.0 software to measure,originating the data of the distance between the area of insula and the midsagittal plane,then we come to the conclusion of 95% confidence interval of typical sections′ distance variations between both sides under analysis of SPSS 13.0 statistical software.Results：On each typical sections,the mean of distances from the midsagittal plaue to central insular sulcus,central insular sulcus,anterior periinsular sulcus and inferior periinsular sulcus is dominant in 88 percent of sections in the left side.Significant left asymmetry were indentified in the central insular sulcus in which Z value from-3 to 15 mm sections,anterior periinsular sulcus in which Z value from 0 to-9 mm sections and inferior periinsular sulcus in which Z value from-9 to 9 mm sections（P0.05-P0.01）.The variation was not significant in the remain sections of sulcus（P0.05）.Conclusions：The left insula and the area of deep structure was structural asymmetry in general pattern.Whether there is founctional asymmetry in the regional structures,and whether structural asymmetry is correlated to other regional structural and founctional asymmetry,depending further study.

关 键 词：脑 岛叶 岛沟 非对称性 横断层图像 解剖学 

分 类 号：R322.81[医药卫生—人体解剖和组织胚胎学]