茶碱分子印迹膜色谱的性能  

Performance of theophylline molecularly imprinted membrane chromatography

作　　者：王靖宇[1,2] 许振良[1,2] 张颖[2] 

机构地区：[1]华东理工大学化学工程联合国家重点实验室,上海200237 [2]华东理工大学化学工程研究所膜科学与工程研发中心,上海200237

出　　处：《膜科学与技术》2010年第5期37-42,共6页Membrane Science and Technology

摘　　要：采用自由基热聚合法在PVDF中空纤维膜表面制备茶碱分子印迹膜,采用SEM测试手段对膜聚合前后的表面形貌进行表征,证明分子印迹膜表面聚合层的存在,并将所得分子印迹膜及空白膜组装成膜组件,以膜色谱形式应用于茶碱和可可碱混合物的萃取分离,比较了相同条件下空白膜和印迹膜对茶碱和可可碱选择性吸附性能,同时考察了不同浓度混合液和不同乙酸酸度的甲醇萃取液对过滤结果的影响.结果表明,印迹膜的选择性因子随混合液浓度和萃取液中乙酸含量的增加而降低.Theophylline molecularly imprinted membrane（MIM） was prepared by thermal initiated free radical polymerization on the surface of PVDF hollow fiber membrane.SEM was used to analyze the surface morphology of the membranes before and after polymerization.The polymeric layer in the MIM was proved by SEM and methanol flux experiments.The modules were assembled to detect the MIM＇s separation performance for THO and TB.Meanwhile,the effect of concentration and acetic acid content in extraction solution on the filtration results was discussed.And it showed that the selectivity of the MIMs decreased with the increase of the concentration of the initial solution and the acetic acid content in extraction solution.

关 键 词：茶碱 可可碱 PVDF中空纤维膜 膜色谱 

分 类 号：O657.7[理学—分析化学]