探索性眼球活动对精神分裂症的诊断作用  

The diagnostic effects of exploratory eye movements on schizophrenia

作　　者：唐仕友[1] 许波[1] 吕天才[1] 朱莉英[1] 程伟[1] 张娅[1] 

机构地区：[1]重庆三峡精神卫生中心,404000

出　　处：《临床精神医学杂志》2010年第5期329-330,共2页Journal of Clinical Psychiatry

摘　　要：目的:验证探索性眼球活动检查对精神分裂症的诊断作用,探讨凝视点数(NEF)和反应性探索评分(RSS)的正常分界值。方法:应用DEM-2000眼动检测仪对299例精神分裂症(患者组)和250名对照者(对照组)进行探索性眼球活动检查,测定NEF和RSS,计算敏感度、特异度。结果:患者组较对照组NEF、RSS显著为低(P<0.01),若以NEF≤27或RSS≤5为正常分界值,其阳性预测值达到70%,阳性似然比达到2.07。结论:探索性眼球活动可以作为精神分裂的辅助诊断指标,以NEF≤27或RSS≤5作为正常分界值,其敏感度、特异度较理想。Objective：To explore the diagnostic effect of explorative eye movements test（ EEM） in schiz-ophrenia,and to clarify the normal boundaries of role of gaze points（ NEF） and reactive search score（ RSS）. Method：DEM-2000 eye movement detectors was used to test the eye movements of 299 patients with schizo-phrenia（ patient group） and 250 normal controls（ control group）. NEF and RSS were measured. The sensitivity and specificity were calculated. Results：The RSS and NEF of patients group were significantly lower than those in the control group（ P 0. 01） ,if the normal boundary value of NEF was set to≤27 or RSS was set to≤ 5,the positive predictive value would be 70% and positive likelihood ratio would be 2. 07. Conclusion：Exploratory eye movements can be served as a diagnostic market of schizophrenia. Set NEF≤27 or RSS≤5 as the normal boundary value can make sensitivity and specificity much more desirable.

关 键 词：精神分裂症 探索性眼球活动 诊断价值 

分 类 号：R749.3[医药卫生—神经病学与精神病学]