自发性低颅压综合征48例临床分析及文献复习  

Clinical analysis of 48 cases of spontaneous intracranial hypotension and a review of literatures

作　　者：张旭[1,2] 陈兴泳[1,2] 雷惠新[1,2] 唐荣华[3] 陈云[3] 

机构地区：[1]福建医科大学省立临床医学院 [2]福建省立医院神经内科,福州350001 [3]华中科技大学同济医学院附属同济医院神经内科

出　　处：《山西医科大学学报》2010年第10期905-907,共3页Journal of Shanxi Medical University

摘　　要：目的分析自发性低颅压综合征(spontaneous intracranial hypotension,SIH)的临床特征、诊断及治疗转归。方法对48例SIH患者的临床资料进行回顾性分析。结果 48例患者均有体位性头痛,多数伴随恶习呕吐等症状,可出现脑膜刺激征;腰穿脑脊液压力<70mmH2O,13例红细胞计数增多,8例总蛋白增高;可并发慢性硬膜下血肿或积液,硬脑膜增厚并强化。充分补液治疗效果好。结论认识SIH的临床特点、发生机制、CSF及影像学特征,可提高SIH的确诊率;本病预后良好。Objective To analyze the clinical characteristics,diagnosis and treatment of spontaneous intracranial hypotension（SIH）.Methods The clinical data of 48 patients with SIH were retrospectively analyzed.The relevant medical literature was reviewed.Results The patients with SIH were characterized by orthostatic headache,nausea,vomiting and meningeal irritation signs.All patients showed low CSF pressure（〈70 mmH2O）.The red blood cell count increased in 13 patients and total protein increased in 8 patients.Some patients were complicated with chronic subdural effusion or hematoma,or diffuse dural enhancement.Conservative management by enough fluid replacement resulted in rapid resolution of symptoms in all patients.Conclusion To know the clinical features,pathogenesis and the features of CSF and imagings in SIH may increase the diagnosis rate.SIH has a good prognosis.

关 键 词：自发性低颅压综合征 体位性头痛 脑脊液 

分 类 号：R741[医药卫生—神经病学与精神病学]