瞬目后不同注视时间的角膜地形图变化  

Corneal topography changes at different time of fixation after blinking

作　　者：王若洁[1] 郑穗联[1] 苏小夏[1] 邱梭[1] 施明光[1] 

机构地区：[1]温州医学院附属二院眼科,325027

出　　处：《中国实用眼科杂志》2010年第10期1064-1066,共3页Chinese Journal of Practical Ophthalmology

摘　　要：目的 分析比较非干眼与干眼瞬目后不同注视时间的角膜地形图变化,以探讨最后一次瞬目后进行角膜地形图摄影的最佳时间.方法 应用角膜地形图仪检测非于眼（30只眼）和干眼（30只眼）,其中非干眼在最后一次完整瞬目后的5s、15s、30s时进行摄影,干眼在正常瞬目情况下,其中一次完整瞬目后的5s进行摄影,分别记录角膜不规则指数（CIM）、形态系数（SF）.结果 非干眼瞬目后5s、15s、30s的CIM值明显增大（P＜O.05）,而SF差异无统计学意义.干眼患者瞬目后5s的CIM、SF值分别1.15±0.55、0.28±0.14.与非干眼相比,平均CIM值明显大于非干眼瞬目后5s的CIM值（P＜0.01）,且大于非干眼瞬目后15s的平均CIM值,小于瞬目后30s的平均CIM值.SF平均值两者无统计学意义（P＞0.05）.结论 （1）角膜地形图测量准确性与测量时注视时间密切相关,建议在最后一次瞬目后5s内进行摄影.（2）角膜表面规则性与泪膜的均匀涂布有关.Objective To analyze and compare the changes of corneal topographic parameters at different time of fixation after blinking between non-dry eyes and dry eyes and to investigate the optimal time between the last blink and the acquisition of topographic image. Methods Thirty non-dry eyes and 30 dry eyes were examined using corneal topography system. Photographs were taken at 5, 15 and 30 seconds after a complete blinking in non-dry eyes and were taken at 5 seconds after the last blinking in dry eyes. The main outcome measures were corneal irregularity measure （CIM） and shape factor （SF）. Results The mean values of CIM increased significantly during the 30 seconds pause in blinking in non-dry eyes （P 〈0.05）. The mean of CIM and SF values were 1.15± 0.55, 0.28± 0.14 at 5 seconds after the last blink in dry eyes, respectively. The mean values of CIM was significantly greater than that at 5S after a complete blinking in non-eyes （P〈0.01）. Conclusions The accuracy of the corneal topography system is closely related to the time of fixation after blinking. It is proposed to perform the topographic measurements within 5 seconds after the last blink. The regularity of corneal surface is correlated with the smooth of the tear film.

关 键 词：瞬目 角膜地形图 角膜表面 干眼 

分 类 号：R778.11[医药卫生—眼科]