Cronkhite-Canada综合征43例临床分析  

Clinical analysis of 43 cases of Cronkhite-Canada syndrome

作　　者：李曼[1] 朱明欣[1] 黄浩[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院第二临床学院,湖北武汉430030

出　　处：《中国现代医学杂志》2010年第18期2806-2808,共3页China Journal of Modern Medicine

摘　　要：目的分析Cronkhite-Canada综合征(CCS)的临床特点。方法报告该院收治的1例CCS患者,并检索1985年1月～2008年12月国内42例CCS患者的临床资料进行临床分析。结果国内43例CCS患者以外胚层变化、胃肠道多发性息肉为主要临床特点,2例患者合并胃肠道肿瘤。19例患者经综合治疗症状不同程度缓解,20例随访患者平均生存时间为15个月。结论 CCS发病率极低,本病的确诊有赖于内镜及组织学检查,目前国内外暂无特异性治疗方案。本病预后不佳,半数患者确诊后2年内死亡。【Objective】 To investigate the clinical feature of Cronkhite-Canada syndrome（CCS）.【Methods】A case of CCS in our hospital was studied and the data of forty-two CCS patients from 1985 to 2008 were retrieved.【Results】The main features of CCS were ectodermal symptoms and gastrointestinal polyposis.Gastrointestinal tu-mors were reported in 2 patients.About 19 patients had symptomatic response to combination therapy.The mean survival time of 20 follow-up patients were 15 months.【Conclusion】CCS is rare.The diagnosis of CCS depends on digestive endoscopy and pathological findings.There is no optimal treatment for CCS.The prognosis is not good and half of the patients die in 2 years after diagnosis.

关 键 词：CRONKHITE-CANADA综合征 胃肠道息肉 临床分析 

分 类 号：R57[医药卫生—消化系统] R758.7[医药卫生—内科学]