初诊脑转移癌全脑放射治疗现状与进展  

The Current Situation and Advances in the Whole Brain Radiation Therapy for Newly-diagnosed Brain Metastases

作　　者：欧丹[1,2] 胡超苏[1,2] 

机构地区：[1]复旦大学附属肿瘤医院放疗科,上海200032 [2]复旦大学上海医学院肿瘤学系,上海200032

出　　处：《中国神经肿瘤杂志》2010年第3期169-176,共8页Chinese Journal of Neuro-Oncology

摘　　要：脑转移癌是最常见的成人颅内肿瘤,采用积极治疗措施可以延长生存时间,提高生活质量。不同预后因素患者需选择个体化治疗模式。本文综述目前初诊脑转移癌全脑放射治疗现状与进展。全脑放疗联合手术或立体定向放疗的治疗模式在延长生存期、改善神经认知功能、提高生活质量方面显示出了很大优势,期望多学科综合治疗研究进展能进一步改善疗效。Brain metastases are the most common intracranial tumors in adult. Available evidence suggests that survival is longer and quality of life is improved when brain metastases are treated aggressively. To select the appropriate therapy, the physician must consider various prognostic factors. In this article, we reviewed current approaches and progress of whole brain radiation therapy （WBRT） in the management of newly diagnosed brain metastases. The combination of WBRT with stereotactic radiosurgery （SRS） or surgery has shown superior results in terms of survival time, neurocognitive function, and quality of life. Further advances in multidisciplinary approaches and optimal dosing/fractionation schedule will result in improved patient outcomes.

关 键 词：脑转移癌 全脑放疗 

分 类 号：R739.41[医药卫生—肿瘤]