血小板与肿瘤转移  

Platelet and tumor metastasis

作　　者：钱雯川(综述)[1] 王凡(审校)[1] 

机构地区：[1]安徽医科大学第一附属医院放疗科,合肥230022

出　　处：《国际肿瘤学杂志》2010年第10期790-791,共2页Journal of International Oncology

摘　　要：血小板可与循环中的肿瘤细胞相互作用形成血小板一瘤栓，帮助肿瘤细胞逃脱免疫系统的攻击。活化的血小板还可释放多种生物活性因子，促进肿瘤细胞的侵袭和生长，诱导肿瘤新血管生成。血小板与肿瘤转移关系的研究，对阐明肿瘤侵袭与转移的机制，建立抗肿瘤转移治疗的新方法具有重要价值。Platelets can interact with circulating tumor cells to form platelet-tumor cell thrombus, which can facilitate the immune evasion of tumor cells. Activated platelets can also release a variety of bioactive factors, promoting tumor growth, invasion and angiogenesis. Research exploring the relationship between plate- let and tumor metastasis can help elucidate the mechanisms of tumor metastasis and find new therapies for treatment of tumor metastasis.

关 键 词：肿瘤转移 血小板 肿瘤循环细胞 

分 类 号：R73-37[医药卫生—肿瘤]