成釉质细胞分化机制的研究进展  

Advance in research of the mechanisms of the ameloblast differentiation

作　　者：林运鸿[1] 刘丽[1] 葛玉强[1] 王也[1] 邓春梅[1] 

机构地区：[1]福建师范大学生命科学学院发育与神经生物学福建省高校重点实验室,福建福州350108

出　　处：《现代生物医学进展》2010年第19期3732-3734,共3页Progress in Modern Biomedicine

摘　　要：牙齿的发育是由牙上皮和神经脊来源的间充质之间的连续的相互诱导产生的。上皮和间充质之间连续的相互诱导,使得上皮细胞分化为具有分泌牙釉质功能的成釉质细胞,而间充质细胞分化为具有分泌牙本质功能的成牙本质细胞。成釉质细胞的正常分化对于形成正常的牙釉质是至关重要的,本文主要对细胞信号分子、细胞黏附分子、釉质特异性基因和转录因子等在成釉质细胞分化过程中的作用做一概述。Tooth development is largely dependent on sequential and reciprocal interactions between dental epithelium and neural crest derived mesenchymal. This process is characterized by events that determine the histodifferentiation of epithelial cells into enamel-secreting ameloblasts and of mesenchymal cells into dentin-secreting odontoblasts. Ameloblast differentiation for the normal formation of normal enamel is crucial, this article on cell signaling molecules, cell adhesion molecules, enamel-specific genes and transcription factors in the process of cell differentiation into enamel to do an overview of the role.

关 键 词：牙齿 牙釉质 成釉质细胞 

分 类 号：R78[医药卫生—口腔医学]