牙齿发育与BMP信号通路的关系  

Relationship between Tooth Development and BMP Signaling Pathway

作　　者：刘丽[1] 林运鸿[1] 邓春梅[1] 王也[1] 

机构地区：[1]福建师范大学生命科学学院发育与神经生物学福建省高校重点实验室,福建福州350108

出　　处：《现代生物医学进展》2010年第19期3760-3761,3767,共3页Progress in Modern Biomedicine

摘　　要：牙齿的发育过程,包括由胚胎早期预定成牙部位到发育形成完整的牙齿,是一个复杂的连续过程,牙齿的发育过程实际上就是牙源性上皮和颅神经嵴来源的牙源性间充质之间的相互作用的结果。骨形态发生蛋白(BMPs)最初被认为是一种具有高效骨诱导性的蛋白,能够诱导未分化的间充质细胞转化形成软骨以及骨组织,之后的研究证明BMPs在胚胎发育过程中起到至关重要的作用。至今为止经过众多科学家的研究,牙齿发育与BMP信号通路的关系已经研究的相当透彻。The process of tooth development, including early embryo development ,is a complex continuous process. Teeth development is actually dependent on sequential and reciprocal epithelial-mesenchymal interactions. Bone morphogenetic proteins （BMPs） was originally considered a highly efficient induction of bone protein and plays an important role in the embryonic development. By the efforts of scientists, tooth development and the BMP signaling pathway has been studied quite thoroughly.

关 键 词：牙齿发育 BMPS SMADS BMP信号通路 

分 类 号：R78[医药卫生—口腔医学]