Synthesis and Antimicrobial Activity of Heterocyclic Compounds Containing Chromene Ring  

作　　者：Enaiat K. Mohamed Wesam S. Shehab 

机构地区：[1]Chemistry Department, Faculty of Science, Zagazig University, Zagazig, Egypt

出　　处：《Journal of Chemistry and Chemical Engineering》2010年第10期26-32,共7页化学与化工（英文版）

摘　　要：Synthesis of some new compounds containing chromene ring are described in this work. They were synthesized in moderate to good yield, started with Condensation of 7-hydroxy-4-methylcoumarin （1） with ethyl bromoacetate furnishes ethyl-2-（4-methyl-2-oxo-2H-chromen-7-yloxy） acetate （2）. The structures of all the new compounds were confirmed using IR, 1H-NMR spectra and micro analysis, selected members of the synthesized compound were screened for antimicrobial activity. They have shown a wide range of activity from one completely inactive compound to medium active ones.

关 键 词：CHROMENE THIAZOLIDINE Oxazolotriazole derivatives antimicrobial activity 

分 类 号：O626[理学—有机化学] S859.796[理学—化学]