In a search for new antimicrobial agents, some new spiro[indol-thiazolidon- 2,4-diones] (6a-c) were synthesized by condensation of 5-substituted isatins 1 with sulfanilamide in MeOH, ...
supported by the National Natural Science Funds of China(21475081);the Natural Science Foundation of Shaanxi Province(2019JM-237);the Graduate Innovation Fund of Shaanxi University of Science and Technology。
In order to understand the chemical-biological interactions governing their activities toward neuraminidase(NA),QSAR models of 28 thiazolidine-4-carboxylic acid derivatives with inhibitory influenza A virus were devel...
A series of novel scaffolds Thiadiazolyl Piperidine, Thiadiazolyl Piperazine, thiadiazolidine, Thiadiazolyl thiazole and Thiadiazolyl-imidazole-Thione were synthesized from cheap, available and biologically active ste...
A series of novel thiazolidinedione-triazole hybrids were synthesized by one pot reaction between thiazolidine-2.4-dione,substituted aryl aldehydes,piopargyl bromide and substituted aryl azides using piperidine,CuSO4...
An extension of the authors' previous discovery of in vitro antitumor activity of substituted thino [2,3-d] prymidine derivatives is reported. The synthesis of some new spirothino [2,3-d] prymidine (4a-f), imidazol...
supported by the National Natural Science Foundation of China (No. 21202110)
In order to understand the chemical-biological interactions governing their activities toward neuraminidase (NA), QSAR models of 28 thiazolidine-4-carboxylic acid derivatives with inhibitory influenza A virus were d...
Supported by National Natural Science Foundation of China and National Key Technologies R and D Program of the 11th five-year plan,No.2009ZX09501-015
AIM: To evaluate the hepatoprotective roles of (Z)- 5-(4-methoxybenzylidene)thiazolidine-2,4-dione (SKLB010) against carbon tetrachloride (CCI4)-induced acute and chronic liver injury and its underlying mecha...
Conventional and microwave assisted synthesis of new series of N-[2-{2-(substituted phenyl)-4-oxo- 5-(substituted benzylidene)-1,3-thiazolidine}-iminoethyl]-2-aminothiazole 5a-Sin have been developed. The cycloadd...
Synthesis of some new compounds containing chromene ring are described in this work. They were synthesized in moderate to good yield, started with Condensation of 7-hydroxy-4-methylcoumarin (1) with ethyl bromoaceta...
support from the National Natural Science Foundation of China (Grant Nos. 20732003 & 20972128)
L-Thiazolidine-4-carboxylic acid monolayer was prepared on gold electrodes through the self-assembly approach.Such novel thioether-based monolayer could efficiently preconcentrate Cu2+,which provided a simple,stable a...