Tuberculosis caused by Mycobacterium(M.)tuberculosis remains a global public health threat.Over the last few decades,anti-tubercular research mainly focused on mechanisms of identifying by which activated macrophages ...
Tuberculosis(TB)is the leading cause of infectious mortality and morbidity in the world,second only to coronavirus disease 2019.Patients with chronic kidney disease and kidney transplant recipients are at a higher ris...
This work was supported by the Program of National Natural Science Foundation of China(Nos.41906090,81874300,42006092,U1706210,41776141 and 41322037);the Program of Natural Science Foundation of Shandong Province of China(Nos.JQ201510 and ZR2019BD047);Key Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education,Hainan Normal University(RDZH2021003);the Taishan Scholars Program,China(No.tsqn20161010).
Further insights on the secondary metabolites of a soft coral-derived fungus Aspergillus versicolor under the guidance of MS/MS-based molecular networking led to the isolation of seven known cycloheptapeptides,namely,...
Background:Phyto-constituents are widely recognized for hepatoprotective effects.Ascorbic acid is extensively studied for the radical scavenging effect.The objective of the present study was to evaluate the hepatoprot...
This retrospective study aims to demonstrate the effect of antitubercular treatment (ATT) on the pregnancy outcomes and prognoses of patients with genital tuberculosis (GTB) who had received laparoscopy and/ or hyster...
Many researches are undertaken to develop antibiotics to treat resistant tuberculosis. This review discusses new trends in research undertaken on new antituberculars reported to date, with a particular attention on th...
Isolated liver tuberculosis is still considered a rare condition and atypical clinical presentation challenges the clinical acumen of the treating physician. Hepatic tuberculosis is usually associated with an active p...
Various recent reports on Tuberculosis have alarmed an increase in the patient class and subsequent death rates across the globe. Over and above the spread of more dangerous and fatal forms of tuberculosis like MDR-TB...
partly supported by Grant from the Instituto Mexicano del Seguro Social (NO.FIS/IMSS/PROT/G12/1126;FIS/IMSS/PROT/G14/1341)
Objective:To estimate to what extent the mixture of ursolic acid and oleanolic acid,in addition to the antitubercular standard regime,affects the hepatotoxicity profile.Methods:Liver injury was induced in male BALB/c ...
A series of Mannich products bearing quinoline nucleus was synthesized, characterized, and evaluated for their in vitro antitubercular activity against Mycobacterium tuberculosis H37Rv. The results showed that compoun...