大肠癌合并糖尿病患者术后并发症发生的相关因素分析  

Correlated factor analysis of postoperative complication of colorectal carcinoma combined with diabetes

作　　者：陈翔[1] 曾小兵[1] 袁杰[1] 陈勇[1] 

机构地区：[1]上海中医药大学附属曙光医院宝山分院外科,上海201900

出　　处：《重庆医科大学学报》2010年第9期1404-1407,共4页Journal of Chongqing Medical University

基　　金：上海市宝山区科学技术发展基金(编号:07-E-14)

摘　　要：目的:探讨影响大肠癌合并糖尿病患者术后并发症发生的危险因素。方法:对2006年1月～2009年12月我院普外科收治的59例大肠癌合并糖尿病患者进行回顾性分析。采用χ2检验对10个临床相关因素进行单因素分析,再进一步行多因素Logistic回归分析。结果:59例患者中24例出现并发症,其发生率为40.7%。单因素分析结果提示合并症、糖化血红蛋白(Glycosylated hemoglobin,HbAc)、体质指数(Body mass index,BMI)、胰岛素抵抗指数(Insulin resistance index,IRI)与术后12h血糖为危险因素(P<0.05)。进一步的多因素Logistic回归分析结果表明术后血糖与稳态模型胰岛素抵抗指标检测(Homeostasis model assessment insulin resistance index,HOMA-IR)是独立的危险因素(P<0.05)。结论:影响大肠癌合并糖尿病患者术后并发症发生率的主要危险因素为术后血糖与胰岛素抵抗。Objective：Correlated factor analysis of postoperative complication of colorectal carcinoma combined with diabetes.Methods：From Jan 2006 to Dec 2009,59 cases of colorectal carcinoma combines with diabetes in our hospital were analyzed retrospectively.The risk factors were examined by chi-square test and multivariate logistic regression analysis.Results：The overall operative complication rate was 40.7%.Univariate analys showed that major risk factors of postoperative complication of the patients were other system diseases,glycosylated hemoglobin,body mass index,insulin resistance index and postoperative serum glucose（P0.05）.Multivariate logistic regression analysis showed that insulin resistance index and postoperative serum glucose were independent risk factors（P0.05）.Conclusion：Postoperative complication of colorectal carcinoma combined with diabetes are closely related to insulin resistance index and postoperative serum glucose.

关 键 词：大肠癌 糖尿病 并发症 

分 类 号：R735.34[医药卫生—肿瘤]