生物酶解技术在中药提取中的应用  

Application of biological enzymatic hydrolysis technology to extraction of traditional Chinese medicine

作　　者：于敬[1] 周晶[1] 

机构地区：[1]天津医科大学药学院,天津300070

出　　处：《现代药物与临床》2010年第5期340-344,共5页Drugs & Clinic

基　　金：天津市科技攻关项目(06YFGPSH02900)

摘　　要：生物酶解技术是基于酶解作用能选择性地破坏植物细胞壁,从而使植物细胞内的成分更容易溶解、扩散的原理而应用于中药有效成分提取的新技术,具有成分浸出率高、减少热敏成分降解、成本低廉、无需特殊设备就能完成等优势,且有大规模工业化生产的潜力。该技术已经广泛用于多糖、生物碱、黄酮、皂苷、蛋白质、有机酸等中药有效成分的提取中,与传统提取技术相比具有明显的优势。综述了近年来生物酶解技术在多糖、生物碱、黄酮类、皂苷类、有机酸类、蛋白质及肽类等中药成分提取中的应用。Enzymolysis can selectively destroy plant cell walls, thus components in the plant cells can be dissolved easily. So biological enzymatic hydrolysis technology has been used to extract active constituents of traditional Chinese medicine. Biological enzymatic hydrolysis technology has many advantages, such as high extraction efficiency, less thermal decomposition of components, low cost, conventional extraction machinery and potential for large industrialized production. Biological enzymatic hydrolysis technology has been used in the extraction ofpolysaccharides, alkaloids, flavonoids, saponins, proteins, organic acids and so on. Comparedwith traditional extraction technology, it has more obvious advantages. This article sums up the application of biological enzymolysis technology in extraction of traditional Chinese medicine.

关 键 词：生物酶 生物酶解技术 提取 中药 纤维素酶 果胶酶 

分 类 号：R284.2[医药卫生—中药学]