^(18)F-FDG PET/CT在甲状腺肿瘤原发灶中的应用及SUVmax界值的探讨  

Preoperative Diagnostic Evaluation and SUVmax Cutoff of the Primary Thyroid Nodules with ^(18)F-FDG PET/CT

作　　者：朱峥嵘[1] 罗灿华[1] 袁建伟[2] 冯彦林[2] 廖珊[3] 

机构地区：[1]广东省佛山市第一人民医院血管甲状腺外科,广东佛山528000 [2]广东省佛山市第一人民医院核医学科,广东佛山528000 [3]广东省佛山市第一人民医院统计室,广东佛山528000

出　　处：《临床医学工程》2010年第9期9-12,共4页Clinical Medicine & Engineering

摘　　要：目的评价18F-FDG PET-CT在甲状腺肿瘤原发灶的诊断价值。方法 45例经术前B超检查,共50个病灶怀疑甲状腺恶性肿瘤纳入研究,术前行18F-FDG PET/CT检查评价良恶性,术后病理诊断作为"金标准",对比、评价18F-FDG PET/CT的诊断价值及探讨SUVmax的最佳诊断界值。结果 50个病灶,病理诊断26例为恶性肿瘤,24例为良性肿物。18F-FDG PET/CT诊断的敏感度为88.5%,特异度为79.2%。恶性组SUVmax高于良性组。SUVmax最佳诊断界值为1.810。结论对于B超怀疑的甲状腺恶性肿瘤,18F-FDG PET/CT有很好的诊断价值,寻找合适的SUVmax界值有助于提高诊断准确性。Objective To evaluate the preoperative diagnostic evaluation of 18F-FDG PET/CT in primary thyroid nodules.Methods A total of 45 patients with 50 nodules suspected thyroid malignant lesions by ultrasonography were obtained the preoperative 18F-FDG PET/CT.The 18F-FDG PET/CT diagnosis was compared with the pathology diagnosis to find out the evaluation of the 18F-FDG PET/CT and the ideal SUVmax cutoff.Results 26 of 50 thyroid nodules were malignant and 24 were benign.Sensitivity was 88.5% and specificity was 79.2% for 18F-FDG PET/CT respectively.The SUVmax of the malignant group was higher than taht of the benign group.The ideal SUVmax cutoff was 1.810.Conclusion 18F-FDG PET/CT provides a potentially high diagnostic evaluation in primary thyroid nodules which were suspected malignant by ultrasonography.Establishing the adequate SUVmax cutoff could improve the diagnostic correct rate.

关 键 词：甲状腺肿瘤 PET/CT 18F-FDG SUVMAX 

分 类 号：R736.1[医药卫生—肿瘤]