小细胞肺癌治疗62例分析  被引量:1

The analysis of different therapy in 62 small cell lung cancer

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作  者:李朝平 张永亮[2] 吉利娜[3] 

机构地区:[1]山西省晋城市人民医院,048000 [2]武警山西总队医院 [3]山西医科大学

出  处:《中国医学创新》2010年第29期83-84,共2页Medical Innovation of China

摘  要:目的比较小细胞肺癌的治疗模式及治疗效果。方法 1、2期小细胞细胞肺癌患者62例A组(32例)行手术治疗,术后给予放化疗,B组(30例)单纯给予放化疗。结果A组中位生存时间为50个月,1、2、3年生存率分别为96%、70%、52%,B组总中位生存时间为48个月,1、2、3年生存率分别为93%、71%、48%;A组术后治疗中或治疗后出现转移病灶的情况依次为:失败原因包括局部复发(12%)、远处转移(32%)、局部复发加远处转移(8%)和脑转移(19%),B组失败原因包括局部复发(14%)、远处转移(30%)、局部复发加远处转移(9%)和脑转移(29%)。手术+化疗+放疗组与放化疗组的生存率差异无统计学意义(P>0.05)。结论手术+化疗+放疗和放化疗对临床Ⅰ、Ⅱ期小细胞肺癌的治疗均有较好的疗效。Objective compare with the therapy method and effect of Small cell lung cancer. Methods 1,2 - small cell lung cancer ceils A group of 62 patients ( 32 patients ) underwent surgery, radiotherapy and chemotherapy were given postoperatively, B group (30 cases) to chemotherapy alone. Results A median survival time was 50 months, 1,2,3 year survival rates were 96% , 70% , 52%, B group overall median survival time was 48 months, 1,2,3 year survival rates were 93%, 71%, 48% ; A group of patients after treatment or treatment of metastatic lesions in the following order: the reasons for failure include the local recurrence (12%) , distant metastasis (32%) , local recurrence plus distant metastasis (8%) and brain metastases ( 19% ) , B group, including the reasons for failure of local recurrence ( 14% ) , distant metastasis (30%), local recurrence plus distant metastases ( 9% ) and brain metastases ( 29 % ). Surgery + chemotherapy + radiotherapy group and the survival rate of radiotherapy and chemotherapy group showed no significant difference ( P 〉 0.05 ). Conclusion Surgical + chemotherapy + radiotherapy and chemotherapy of clinical stage I , II small cell lung cancer have good prognosis.

关 键 词:小细胞肺癌 手术 化疗 

分 类 号:R734.2[医药卫生—肿瘤]

 

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