食管癌高发区玉米中伏马菌素B1的检测  

The Determination of FumonisinB1 in Corn from High Ri

作　　者：王海涛[1] 魏慧娟[1] 马吉林 罗贤懋[1] 

机构地区：[1]中国医学科学院肿瘤研究所

出　　处：《肿瘤防治研究》1999年第3期168-170,共3页Cancer Research on Prevention and Treatment

基　　金：国家九五攻关基金

摘　　要：目的：检测串珠镰刀菌主要代谢产物ＦｕｍｏｎｉｓｉｎＢ１在华北食管癌高发区玉米中的含量并比较高发区和低发区的含量差别。方法：反相高效液相色谱柱前衍生荧光法。结果：正常玉米ＦＢ１的阳性率为９０９０％，平均含量为１４０±０５０μｇ／ｇ。霉变玉米的阳性率为１００％，平均含量为８８９１±１３０７μｇ／ｇ。结论：高发区的串珠镰刀菌污染率和ＦＢ１含量比较高。Objective:to determine the content of Fumonisin B1 in corn from high risk area of esophageal cancer and compare the content difference between the high risk and the low risk areas of esophageal cancer.Methods:reversed phase high performance liquid chromatography with fluorescence detector.Results:The positive detection rates of FumonisinB1 in moldy and fine samples were 100% and 90 90%,respectively.The average content of FumonisinB1 in moldy corn samples is 88 90±13 1μg/g,and the apparently healthy corn samples is 1 40±0 50μg/g.Conclusion:The frequency of FumonisinB1 contamination and content in corn from high risk area are very high,it may be involved in etiology of esophageal cancer.

关 键 词：食管癌 玉米 伏马菌素B1 高效液相色谱 

分 类 号：R735.1[医药卫生—肿瘤]