参蛇偏瘫胶囊治疗进展性脑梗死的临床研究  

Clinical Curative Effect of Shenshe Hemiplegia Capsule For Progress Of Cerebral Infarction

作　　者：张红瑞[1] 周红霞[2] 徐周扬[3] 

机构地区：[1]河南中医学院,河南郑州450008 [2]河南中医学院第一附属医院,河南郑州450000 [3]郑州市中心医院,河南郑州450007

出　　处：《中医学报》2010年第6期1157-1159,共3页Acta Chinese Medicine

摘　　要：目的:观察参蛇偏瘫胶囊治疗进展性脑梗死的临床疗效。方法:采用随机、双盲、对照的临床研究方法,选择发病72h内确诊的脑梗死患者120例,随机平均分为参蛇偏瘫胶囊组和对照组,进行临床及实验室指标观察并进行比较。结果:参蛇偏瘫胶囊组和对照组有效率分别为98.33%和88.33%(P<0.01)。参蛇偏瘫胶囊组治疗前后,神经功能缺损评分明显减小,血小板聚集率、全血粘度、血浆粘度明显降低(P<0.01);与对照组比较,差异有统计学意义(均为P<0.05)。两组纤维蛋白原的变化不显著(P>0.05)。结论:参蛇偏瘫胶囊治疗进展性脑梗死安全有效,能有效改善脑血管血流动力学指标(CVHI)。Objective ： To observe the clinical curative effect of shenshe hemiplegia capsule for progress of cerebral infarction. Methods ： Using randomized, double - blind, controlled clinical research method, 120 cases of disease within 72 h diagnosis in patients with cer- ebral infarctioneases were randomly divided into two groups, and shenshe snake hemiplegia capsule group and control group 60 pa- tients, doing clinical observation and comparison laboratory index. Results ： An total effectivene rate of shenshe snake hemiplegia capsule group and control group was 98.33%, 88.33% respectively P 〈 0.01 ）. And snake hemiplegia capsule group before and after treatment, neurologic deficits score, platelet aggregation rate, the whole blood viscosity, plasma viscosity decreased significantly （ P 〈 0.01 ）, Compared with controls, there are a statistically significant （P 〈0.05 ）. Two groups of fibrinogen changes are not significant （P 〉 0.05 ） . Conclusion： Shenshe hemiplegia capsule for progress sex straightens dead is safe and effective, and can effectively improve cardiovascular hemodynamics index （CVHI）.

关 键 词：中风 进展性脑梗死 参蛇偏瘫胶囊 

分 类 号：R743.3[医药卫生—神经病学与精神病学]