Circadian regulation of Limulus visual functions:A role for octopamine and cAMP  

作　　者：Jasbir S.DALAL Barbara-Anne BATTELLE 

机构地区：[1]Whitney Laboratory for Marine Bioscience and the Departments of Neuroscience and Biology, University of Florida [2]Department of Internal Medicine and Division of Human Nutrition and Metabolic Diseases, University of Texas Southwestern Medical Center

出　　处：《Current Zoology》2010年第5期518-536,共19页动物学报（英文版）

基　　金：supported by grants from the National Science Foundation (NSF);the Whitehall Foundation and the Whimey Laboratory

摘　　要：The purpose of this contribution is to review our current understanding of the source and biochemistry of the circadian efferent input to the eyes of the American horseshoe crab Limuluspolyphemus and the impact of this input on the structure, physiology and biochemistry of Limulus eyes. Special emphasis is given to the role of the biogenic amine octopamine and bio- chemical cascades it activates in the eyes. In addition to reviewing published data, we present new data showing that octopamine elevates cAMP levels in Limulus lateral eyes, and we partially characterize the pharmacology of the receptors involved in this response. We also present new data showing that octopamine regulates gene expression in Limulus lateral eyes by activating a cAMP cascade

关 键 词：Horseshoe crab Circadian rhythms Oetopamine PHOTORECEPTORS Substance P ARRESTIN 

分 类 号：Q436[生物学—生理学]