PHOTORECEPTORS

作品数：38被引量：79H指数：4
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相关领域：医药卫生更多>>
相关作者：郭文毅吴继红方媛张卯年莫晓芬更多>>
相关机构：北京大学重庆医科大学复旦大学中国人民解放军总医院更多>>
相关期刊：《International Journal of Ophthalmology(English edition)》《Chinese Medical Journal》《Neural Regeneration Research》《Current Zoology》更多>>
相关基金：国家自然科学基金以色列科学基金国家重点基础研究发展计划更多>>
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Optimal transcorneal electrical stimulation parameters for preserving photoreceptors in a mouse model of retinitis pigmentosa
《Neural Regeneration Research》2024年第11期2543-2552,共10页Sam Enayati Karen Chang Anton Lennikov Menglu Yang Cherin Lee Ajay Ashok Farris Elzaridi Christina Yen Kasim Gunes Jia Xie Kin-Sang Cho Tor Paaske Utheim Dong Feng Chen 
supported by The Norwegian Research Council;Department of Ophthalmology,Oslo University Hospital,Oslo,Norway(to TPU);Department of Medical Biochemistry,Oslo University Hospital,Oslo,Norway(to TPU);The Norwegian Association for the Blind and Partially Sighted(to TPU);The Ministry of Science and Technology of Taiwan,China MOST 105-2917-I-002-031,MOST 109-2917-I-564-032(to KC);The Scientific and Technological Research Council of Turkiye-TUBITAK(to KG);BrightFocus Foundation(to KSC);the Massachusetts Lions Foundation(to KSC);National Eye Institute Grant EY031696(to DFC);Harvard NeuroDiscovery Center Grant(to DFC);Department of Defense(USA)HT9425-23-1-1045(to DFC and AL);Core Grant for Vision Research from NIH/NEI to the Schepens Eye Research Institute(P30EY003790);South-Eastern Norway Regional Health Authority and the Norwegian Society of the Blind(to TPU).
Retinitis pigmentosa is a hereditary retinal disease that affects rod and cone photoreceptors,leading to progressive photoreceptor loss.Previous research supports the beneficial effect of electrical stimulation on pho...
关键词：bipolar cells electrical stimulation NEUROPROTECTION photoreceptor degeneration RETINA retinal explants retinitis pigmentosa transcorneal electrical stimulation WAVEFORM 
Lycium barbarum glycopeptide(wolfberry extract)slows N-methyl-N-nitrosourea-induced degradation of photoreceptors被引量：1
《Neural Regeneration Research》2024年第10期2290-2298,共9页Qihang Kong Xiu Han Haiyang Cheng Jiayu Liu Huijun Zhang Tangrong Dong Jiansu Chen Kwok-Fai So Xuesong Mi Ying Xu Shibo Tang 
supported by Guangzhou Key Projects of Brain Science and Brain-Like Intelligence Technology,No.20200730009 (to YX);the National Natural Science Foundation of China,No.82074169 (to XM);the Guangdong Basic and Applied Basic Research Foundation,No.2021A1515012473 (to XM);Project of Administration of Traditional Chinese Medicine of Guangdong Province,No.20202045 (to XM);Aier Eye Hospital Group,No.AF2019001 (to ST,KFS,YX,XM)。
Photoreceptor cell degeneration leads to blindness, for which there is currently no effective treatment. Our previous studies have shown that Lycium barbarum(L. barbarum) polysaccharide(LBP) protects degenerated photo...
关键词：anti-inflammation inherited retinal diseases Lycium barbarum glycopeptide N-METHYL-N-NITROSOUREA OPSIN photoreceptor reactive gliosis retinal degeneration retinitis pigmentosa RHODOPSIN 
Extracellular vesicles as a potential therapeutic for age-related macular degeneration被引量：1
《Neural Regeneration Research》2023年第9期1876-1880,共5页Lorraine L.C.Chow Ben Mead 
Age-related macular degeneration is a major global cause of central visual impairment and seve re vision loss.With an aging population,the already immense economic burden of costly anti-vascular endothelial growth fa ...
关键词：age-related macular degeneration EXOSOMES extracellular vesicles MIRNA NEUROPROTECTION PHOTORECEPTORS RETINA retinal pigment epithelium 
Significant impact of deprotonated status on the photoisomerization dynamics of bacteriophytochrome chromophore被引量：1
《Chinese Chemical Letters》2023年第7期428-433,共6页Haiyi Huang Chao Xu Kunni Lin Jiawei Peng Feng Long Gu Zhenggang Lan 
supported by National Natural Science Foundation of China (NSFC, Nos. 21903030, 21933011 and 21873112)。
We report that the photoinduced dynamics of the phytochrome chromophore is strongly dependent on the protonation/deprotonation states of the pyrrole ring. The on-the-fly surface hopping dynamics simulations were perfo...
关键词：PHOTOCHEMISTRY PHOTORECEPTORS Excited states Non-adiabatic dynamics Conical intersection 
Neural and Müller glial adaptation of the retina to photoreceptor degeneration被引量：2
《Neural Regeneration Research》2023年第4期701-707,共7页Henri O.Leinonen Edward Bull Zhongjie Fu 
supported by NIH R01EY032492;Boston Children’s Hospital(OFD/BTREC/CTREC Faculty Career Development Grant 97906,Pilot Grant 92214,and Ophthalmology Foundation 85010);Mass Lions Eye Foundation 87820;Blind Children’s Center 89282(to ZF);Academy of Finland grant 346295;Finnish Eye and Tissue Bank Foundation;Retina Registered Association(Finland);Sokeain Yst?v?t/De Blindas V?nner Registered Association(to HOL)。
The majority of inherited retinal degenerative diseases and dry age-related macular degeneration are characterized by decay of the outer retina and photoreceptors,which leads to progressive loss of vision.The inner re...
关键词：bipolar cells ELECTRORETINOGRAPHY Müller glia PHOTORECEPTORS plasticity retinal degeneration retinal neuron retinal remodeling retinal ganglion cells 
Controlled LED Lighting for Horticulture: A Review
《Open Journal of Applied Sciences》2023年第2期175-188,共14页Emmanouil D. Fylladitakis 
As energy gradually becomes a more valuable commodity, the desire for reduced energy losses strengthens. Lighting is a critical field on this matter, as it accounts for a large percentage of the global electricity con...
关键词：Horticulture Lighting Agriculture Lighting Controlled LED Light Light Wavelength Effects Light Spectrum VEGETABLES CROPS PHOTORECEPTORS 
Control of Plant Growth and Defense by Photoreceptors: From Mechanisms to Opportunities in Agriculture被引量：1
《Molecular Plant》2022年第11期1825-1825,共1页Ronald Pierik Carlos L.Ballaré 
(Molecular Plant 14,61-76;January 42021)After publication of our original manuscript,we became aware of an error in Figure 2.The red connector that indicates reciprocal repression on the right-hand side of the figure ...
关键词：FIGURE Plant ERROR 
The future of retinal gene therapy: evolving from subretinal to intravitreal vector delivery被引量：4
《Neural Regeneration Research》2021年第9期1751-1759,共9页Maya Ross Ron Ofri 
funded by grants from the Israel Science Foundation(1257/15);the Chief Scientist Office,Ministry of Health(3-15068),awarded to RO。
Inherited retinal degenerations are a leading and untreatbale cause of blindness, and as such they are targets for gene therapy. Numerous gene therapy treatments have progressed from laboratory research to clinical tr...
关键词：adeno-associated virus animal model BLINDNESS gene therapy inner limiting membrane PHOTORECEPTORS RETINA retinitis pigmentosa VITREOUS 
Inhibition of mTOR signaling by rapamycin protects photoreceptors from degeneration in rd1 mice被引量：1
《Zoological Research》2021年第4期482-486,共5页Jia-Liang Yang Tong-Dan Zou Fang Yang Zheng-Lin Yang Hou-Bin Zhang 
supported by the National Precision Medicine Project(2016YFC0905200)(Z.Y.&H.Z.);National Natural Science Foundation of China(81570882(H.Z.),81770935(H.Z.));Department of Science and Technology of Sichuan Province,China((2020YJ0445)(H.Z.),2020ZYD037(Z.Y));CAMS Innovation Fund for Medical Sciences(2019-I2M-5-032)(Z.Y.)。
Retinitis pigmentosa(RP)is an inherited retinal degenerative disease that begins with defective rod photoreceptor function,followed by impaired cone function,and complete blindness in its late stage.To date,however,th...
关键词：DEGENERATION RAPAMYCIN IMPAIRED 
The neuroprotective role of Wnt signaling in the retina被引量：2
《Neural Regeneration Research》2021年第8期1524-1528,共5页Stefan Kassumeh Gregor R.Weber Matthias Nobl Siegfried G.Priglinger Andreas Ohlmann 
supported by the Deutsche Forschungsgemeinschaft(OH 214/4-3,FOR 1075,TP7)。
The canonical Wnt/β-catenin signaling pathway has been shown to play a major role during embryonic development and maturation of the central nervous system including the retina. It has a significant impact on retinal...
关键词：apoptosis β-catenin leukemia inhibitory factor Müller cells NEURODEGENERATION NEUROPROTECTION Norrin PHOTORECEPTORS RETINA retinal ganglion cells WNT 
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