用二项分布分析乙肝病毒感染标志的家族聚集性  

FAMILIAL AGGREGATION STUDIES OF SIGNS OF HEPATITIS B VIRUS INFECTION BY BINOMIAL DISTRIBUTION

作　　者：梁雪枫[1] 高丽[1] 刘建峰[1] 甄晓荣[1] 张晓曙[1] 傅鸿 李慧[1] 

机构地区：[1]甘肃省疾病预防控制中心,兰州730000

出　　处：《现代预防医学》2010年第22期4208-4210,共3页Modern Preventive Medicine

摘　　要：[目的]研究甘肃省乙肝病毒感染标志的分布是否有家庭聚集性。[方法]2006年甘肃省乙肝血清流行病学抽样调查949户家庭,其中有605个乙肝病毒感染标志阳性病例,分布在398户家庭。本研究针对该数据,采用二项分布进行拟合。如果该数据不服从二项分布,则乙肝表面抗原的分布呈家庭聚集性。[结果]利用二项分布进行拟合,所得统计学检验P值分别为0.000 0,表明该数据不服从二项分布。[结论]甘肃省乙肝感染标志的分布呈家庭聚集性。[Objective] To analyze the familial aggregation of hepatitis B virus infection sign in Gansu province.[Meth-ods] In 2006,949 families were sampled in Gansu sampling survey of hepatitis B virus surface antigen.Among them,there were 605 patients distributed in 398 families.The data was analyzed by fitting binomial distribution.If the data did not follow the binomial distribution,then the infection of Signs of hepatitis B virus infection had a phenomenon of familial aggregation.[Re-sults] P Values for fitting binomial distribution were 0.000 0,which indicated the data did not follow the binomial distribution.[Conclusion] The Signs of hepatitis B virus infection in Gansu province has a phenomenon of familial aggregation.

关 键 词：乙肝病毒感染标志 家庭聚集性 二项分布 

分 类 号：R512.62[医药卫生—内科学]