广州市成人非酒精性脂肪性肝病患病分析  

Prevalence of nonalcoholic fatty liver disease in adults of Guangzhou city

作　　者：林妙霞[1] 罗敏琪[2] 余超[1] 王自明[1] 何娅娣[1] 朱婉丽[1] 王小红[1] 

机构地区：[1]中山大学附属第三医院体检中心,广州510630 [2]中山大学附属第三医院检验科

出　　处：《中国公共卫生》2010年第11期1418-1419,共2页Chinese Journal of Public Health

基　　金：广东省科技计划项目(2009B030801008)

摘　　要：目的探讨健康体检人群中非酒精性脂肪性肝病(NAFLD)患病及相关危险因素,为临床预防及控制提供科学依据。方法采用横断面调查研究方法,以810名健康体检人群为研究对象,收集相关的临床资料进行统计学分析。结果 NAFLD患病142例,总患病率为17.5%,男性98例,患病率为20.9%,女性44例,患病率为12.9%,不同性别间差异有统计学意义(P<0.01);多因素Logistic回归分析结果显示,体质指数、甘油三酯、空腹血糖、舒张压、年龄、谷丙转氨酶、饮食习惯及运动锻炼与NAFLD发病有关(P<0.05)。结论广州市成人NAFLD患病率较高;超重或肥胖,甘油三酯、空腹血糖、舒张压及谷丙转氨酶升高,年龄较大、高脂饮食及缺乏运动锻炼是NAFLD患病的独立危险因素。Objective To estimate the prevalecne of nonalcoholic fatty liver disease（NAFLD） and its risk factors among the people took physical examination and to provide scientific bases for clinical prevention and treatment of the dis-ease.Methods The physical examination results of 810 people from Jan 2009 to Dec 2009 were collected and analyzed.Results The total incidence rate of NAFLD was 17.5%.The incidence rate of the male（20.9%） was higher than that of the female（12.9%）（P 0.01）.Multivariate logistic regression analysis showed that NAFLD was significantly related to body mass index,triglycerides,fasting blood glucose,diastolic blood pressure,age,alamine amiotransferase,eating habit,and exercise（P 0.05 for all）.Conclusion NAFLD is prevalent in residents of Guangzhou city.Overweight or obesity,high trighyceride,fast blood glucose,diastolic blood pressure,alamine aminotransferase,aging,eating high fat food,and lack of exercise are the independent risk factros of NAFLD.

关 键 词：非酒精性脂肪性肝病 患病率 LOGISTIC回归分析 

分 类 号：R575.5[医药卫生—消化系统]