葡萄膜恶性黑色素瘤眼外蔓延  

Extraocular extension of malignant uveal melanoma

作　　者：张虹[1] 宋国祥[1] 何彦津[1] 田文芳[1] 

机构地区：[1]天津医科大学第二医院眼科

出　　处：《中华眼底病杂志》1999年第1期30-32,共3页Chinese Journal of Ocular Fundus Diseases

摘　　要：目的观察葡萄膜恶性黑色素瘤眼外蔓延的发生率、与病理组织学的关系、临床和影像学特征以及影响预后的因素。方法采用我院２０年间诊治的葡萄膜恶性黑色素瘤眼外蔓延９例进行回顾性分析。所有病例均经病理组织学确诊。结果葡萄膜恶性黑色素瘤眼外蔓延的发生率为１５％。肿瘤在眼内呈扁平状生长者６例，蕈状生长者２例；上皮细胞型４例，梭形细胞型１例。本组随访患者５例表明预后与肿瘤大小、眼外蔓延程度、病理组织学分型有关。结论葡萄膜恶性黑色素瘤早期可向眼外蔓延，并与病理组织学分型有关。Objective To observe the incidence of extraocular extension of malignant uveal melanoma,the relationship between the incidence and histopathologic type,the characters of clinical manifestation and iconography,and the factors influencing prognosis. Methods Nine cases of extraocular extension of malignant uveal melanoma within last 20 years were analyzed retrospectively.All cases were diagnosed by histopathological examination and most of them had undergone ultrasound and CT examinations. Results The incidence of extraocular extension of malignant uveal melanoma was 15%.Tumors of 6 patients were flat and 2 nodular in shape,4 epithelial cell and l spindle cell in type.The follow up results of 5 patients in this series indicated that the prognosis was related to the size of the tumor,the degree of extraocular extension,and histopathologic type. Conclusion Extraocular extension of malignant uveal melanoma might happen in early case and the occurrence is usually related to the histopathologic type of the tumor.Iconographic examination is very helpful for diagnosis in extraocular extension of this tumor.

关 键 词：黑色素瘤 病理学 葡萄膜肿瘤 眼外蔓延 

分 类 号：R739.702[医药卫生—肿瘤] R739.5[医药卫生—临床医学]