34例乳腺癌术后肝转移治疗的临床研究  

Clinical effect of treatment of liver metastasis after breast cancer operation in 34 cases

作　　者：陈中皓[1] 

机构地区：[1]上海市长宁区中心医院外科,上海200336

出　　处：《中国现代医学杂志》2010年第19期2988-2990,共3页China Journal of Modern Medicine

摘　　要：目的总结探讨乳腺癌术后肝转移的治疗效果。方法回顾性分析34例乳腺癌术后肝转移患者的临床资料,比较单纯的全身化疗(19例)和全身化疗+肝动脉栓塞灌注化疗(15例)两种治疗方法的疗效及预后。结果 34例患者中,经治疗有效17例,其中单纯全身化疗组有效8例(42.1%),全身化疗+肝动脉栓塞灌注化疗组有效9例(60.0%),全身化疗+肝动脉栓塞灌注化疗组有效率高于全身化疗组,但差异无显著性(P>0.05)。34例患者的随访期截止2010年3月,中位生存期为17个月(4～58个月),1、2和3年生存率分别为38.5%、19.1%和14.8%。结论对于乳腺癌术后肝转移的患者,采取恰当有效的治疗方法可以有效缓解病情,提高生存率。【Objective】To summarize treatment of liver metastasis from breast cancer.【Methods】Clinical data of 34 cases with liver metastasis from breast cancer were retrospectively analyzed.The efficacy and prognosis of chemotherapy alone（19 cases） were compared with those of systemic chemotherapy combined with hepatic artery embolization chemotherapy（15 cases）.【Results】The treatment was effective in 17 of the 34 cases,in which 8 cases（42.1%） had simple systemic chemotherapy and 9 cases（60.0%） had combined chemotherapy and hepatic artery embolization chemotherapy.The effective rate was higher in combined systemic chemotherapy and hepatic artery embolization chemotherapy group than in simple systemic chemotherapy group but without significant difference（P 0.05）.The follow-up period in 34 patients ended in March 2010,the median survival period was 17 months（4～58 months）,1-,2-,3-year survival rates were 38.5%,19.1% and 14.8%.【Conclusions】For breast cancer patients with liver metastasis,to take appropriate and effective palliative treatment can improve survival rates.

关 键 词：乳腺肿瘤 手术后肝转移 全身化疗 肝动脉栓塞灌注化疗 

分 类 号：R737.9[医药卫生—肿瘤]