响应面法优化化香树果序多酚的提取工艺研究  

Optimization for extraction of polyphenol from infructescence of Platycarya strobilacea Sieb. et Zucc by response surface method

作　　者：刘明霞[1] 李稳宏[1] 朱忠伟[1] 李冬[1] 林亮[1] 吴俊锋 

机构地区：[1]西北大学化工学院,陕西西安710069 [2]西安长庆科技工程有限责任公司,陕西西安710021

出　　处：《中成药》2010年第11期1891-1894,共4页Chinese Traditional Patent Medicine

基　　金：陕西省教育局重大产业化项目(2007JC18);西安市科技创新支撑计划(F07071)

摘　　要：目的:确定化香树果序中酚类化合物的提取方法并得到最佳提取工艺条件。方法:以化香树果序为原料,在单因素实验基础上根据中心组合(Box-Benhnken)实验设计原理,对提取温度、溶剂浓度、料液比3个影响显著因素采用三因素三水平的响应面分析法对酚类化合物的工艺过程进行优化。结果:得到最佳提取工艺条件为提取温度77℃,溶剂浓度55%,液料比C=14 mL/g,多酚提取率为3.746%。结论:首次从化香树果序中提取分离出了多酚类化合物,通过实验分析得到一条最佳的提取工艺路线。AIM：To study the separation of polyphenol from infructescence of Platycarya strobilacea Sieb.et Zucc and to obtain optimal conditions.METHODS：According to the central composite experimental design princi-ples and one-factor test,the optimal extraction condition was determined by the method of response surface analysis（RSA） with three factors and three levels.The three factors were temperature,alcohol volume fraction and ratio of solvent and material.RESULTS：The optimal extraction parameters were as follows：alcohol volume fraction 55%,temperature 77 ℃ and the ratio of solvent and material 14 mL/g,the extraction rate of total polyphenol could be up to 3.746%.CONCLUSION：It’s easy to get an optimal extraction process by exprement analysis.It is the first time to extract and isolate phenolic compounds from Platycarya strobilacea Sieb.et Zucc infructescence.

关 键 词：化香树 果序 多酚 响应面 

分 类 号：R284.2[医药卫生—中药学]