螺旋CT动态增强扫描在非小细胞肺癌中的应用价值  

The value of dynamic enhanced CT in non-small cell lung cancer

作　　者：李功杰[1] 乔鹏岗[1] 田宁[1] 马锦林[1] 李明[1] 盛复庚[1] 邢旭东[1] 

机构地区：[1]解放军第307医院放射科,北京100071

出　　处：《医学影像学杂志》2010年第10期1446-1448,共3页Journal of Medical Imaging

摘　　要：目的:探讨非小细胞肺癌的螺旋CT动态增强扫描定量参数特点,并结合国内外文献讨论其临床意义。方法:分析61例非小细胞肺癌病灶的螺旋CT动态增强扫描定量参数,重点观察病灶动态增强各时相的CT值,根据CT值绘出动态增强曲线,记录强化峰值(PH)、肿块强化达到峰值时间(Tp),计算肿块与主动脉强化峰值之比(M/A)、灌注值。结果:肺癌病灶增强后CT值立即升高,75s左右形成强化高峰,然后逐渐下降,平均达峰时间(76.25±27.52)s;TDC形态为较快上升-缓慢下降型或较快上升-平台型;最大增强幅值范围17HU^122HU,平均为(47.36±18.28)HU;M/A平均值为0.22±0.08;灌注值平均为(0.26±0.11)ml.min-1.ml-1。结论:肺癌螺旋CT动态强化特点是强化效应较明显,最大增强值多在20HU以上,峰值到达时间多在2min以内,其时间一密度曲线为较快上升-缓慢下降型或较快上升-平台型,这些强化特点具有一定的临床应用价值。Objective：To evaluate the characteristics of dynamic enhanced CT in non-small cell lung cancer and to review related medical science literature to discuss its clinical value.Methods：We analyzed the spiral CT dynamic enhancement findings of 61 non-small cell lung cancer cases,observed the CT values of the lesion in each time,and drew enhancement time-density curves.The functional parameters,i.e.,peak height（PH）,the time to peak height（Tp）,the ratio of PH of the mass to aorta（M/A） and perfusion,were calculated.Results：The CT values of the 61 cases were rapidly increased and slowly decreased or not decreased,average value of the PH was（47.36±18.28） HU,average value of the Tp was 76.25±27.52 s,average value of the M/A was 0.22±0.08,average value of the perfusion was（0.26±0.11） ml·min-1·ml-1.Conclusion：The CT enhanced degree of non-small cell lung cancer is obvious,its largest enhancement value is mostly more than 20 HU,the maximum value often appears not more than 2 min,and the time-density curves often shows rapidly increased and slowly decreased or not decreased,the dynamic enhanced characteristics is helpful in clinical diagnosis.

关 键 词：肺癌 体层摄影术 X线计算机 动态增强 

分 类 号：R734.2[医药卫生—肿瘤] R814.42[医药卫生—临床医学]