胰腺癌90例临床分析  

A clinical study of 90 patients with pancreatic carcinoma

作　　者：邹德龄[1] 刘维波[1] 王灿阳[1] 李跃辉[1] 

机构地区：[1]福建省晋江市医院肿瘤外科,362200

出　　处：《中国综合临床》2010年第11期1196-1197,共2页Clinical Medicine of China

摘　　要：目的 总结胰腺癌的临床特点,以提高对胰腺癌的早期诊断率,并探讨影响胰腺癌的预后因素.方法 采用回顾性分析方法,分析我院1989～2005年的90例胰腺癌患者的临床资料.结果 胰腺癌症状复杂,临床症状以腹痛、黄疸、体重减轻最常见.胰腺癌体征主要有腹部压痛、腹部肿块、肝大、胆囊增大;黄疸是胰头癌的突出表现.手术切除率为17.8%.90例随访资料齐全的病例中,1、3、5年生存率分别为22.2%、11.1%、2.2%.影响生存期的因素为手术方式、肿瘤大小、肿瘤分化程度、TNM分期.结论 胰腺癌的临床表现与病期早晚、癌肿位置、组织学类型、伴随疾病有关.临床症状仅为胰腺癌的诊断提供线索,实验室和影象学检查可为进一步筛选和确诊提供客观依据,并可分析影响胰腺癌预后的因素.Objective To improve the early diagnosis and prognosis factor of pancreatic carcinoma by summarizing and analyzing the clinical data. Methods The clinical data of 90 patients with pancreatic carcinoma of our hospital from 1989 to 2005 were analyzed retrospectively. Results The symptoms of pancreatic carcinoma were very complicated,the most common manifestations were bellyache,jaundice and weight loss. Main physical signs in these patients included abdominal tenderness,abdominal mass,hepatomegalia,gallbladder enlargement. Jaundice was the outstanding manifestation of pancreatic head cancer. Among all patients,16 cases accepted sugical resection（17.8%）,and the 1-year,3-year,5-year survival rate were 22. 2%,11.1% and 2. 2% respectively. Our data showed that the most important prognostic factors which influenced life span were the surgical procedures,tumor size and location,histological differentiation,TNM stage. Conclusions Clinical manifestations of pancreatic carcinoma are related to TNM stage,tumor size and location,histology type,complication disease. Clinical symptoms only provide clue for diagnosis of pancreatic carcinoma. Laboratory and imaging examination will provide objective evidence for further diagnosis and prognosis in pancreatic carcinoma.

关 键 词：胰腺癌 生存期 临床特点 

分 类 号：R735.9[医药卫生—肿瘤]