泮托拉唑预防危急重症并发SU的临床观察234例  

The clinical observation of pantoprazole to prevent the occurrence of stress ulcer in critical patients.

作　　者：肖旭[1] 胡卫健[1] 

机构地区：[1]四川省人民医院急救中心,四川成都610072

出　　处：《四川医学》2010年第11期1623-1624,共2页Sichuan Medical Journal

摘　　要：目的观察泮托拉唑对危急重症患者预防应激性溃疡的效果。方法选择危重病患者234例,随机分为泮托拉唑(观察组)118例,不用泮托拉唑组(对照组)116例。观察两组应激性溃疡的发生率及病死率。结果观察组有效预防危重病患者应激性溃疡的发生(P<0.01)及降低病死率(P<0.05)。结论泮托拉唑是危急重症患者预防应激性溃疡的发生并降低病死率的理想药物。Objective To observe the clinical effects of pantoprazole to prevent the occurrence of stress ulcer in critical patients.Methods234 cases of critical patients were randomly divided into two groups：pantoprazole group（n=120）and control group（n=116）.Incidence rate of stress ulcer and mortality were observed.ResultsThere were lower incidence rate of stress ulcer（P0.01）and mortality（P0.05） in pantoprazole group.Conclusion Pantoprazole is an ideal drug to prevent the occurrence of stress ulcer and reduce mortality in critical patients.

关 键 词：泮托拉唑 危急重症 应激性溃疡 预防 

分 类 号：R573.1[医药卫生—消化系统]