以肝组织为主要成分的纵膈畸胎瘤1例报道及文献回顾  

Mediastina teratoma with the main component of hepatic tissue:a case report and review of literature

作　　者：韩秀娟[1] 李艳红 巩丽[1] 薛力[1] 朱少君[1] 姚丽[1] 刘小艳[1] 张伟[1] 兰淼[1] 

机构地区：[1]第四军医大学唐都医院病理科,陕西西安710038 [2]第四军医大学唐都医院妇产科,陕西西安710038

出　　处：《现代肿瘤医学》2010年第11期2179-2181,共3页Journal of Modern Oncology

摘　　要：目的:报道1例以肝组织为主要成分的纵膈成熟型囊性畸胎瘤,并结合文献探讨其临床及组织病理学特点。方法:对1例以肝组织为主要成分的纵膈成熟型囊性畸胎瘤进行常规病理及免疫组化观察。结果:显微镜下见瘤组织内含有三个胚层衍生物,但大部分区域以肝组织为主。免疫组织化学染色:以肝组织为主区结果示Hepatocyte(+)、AFP(+)、GP3(+)、CK18(+);NSE(-)、Syn(-)、CgA(-)、CD99(-)、CD30(-)、LCA(-)及V im entin(-)。结论:纵膈畸胎瘤较为常见,但以肝组织为主的成熟型囊性畸胎瘤极为罕见。Objective：To report one case of mature cystic teratoma with the main component was hepatic tissue occurring in mediastina and study its clinical and pathological features.Methods：The mediastinal mature cystic teratoma was investigated by histopathologic and immunohistochemical observation.Results：Microscopically,the teratoma had derivants from three germ layers,and the main component was hepatic tissue.In immunohistochemistry,the hepatic cells were positive for Hepatocyte,AFP,GP3 and CK18,but negative for NSE,Syn,CgA,CD99,CD30,LCA and Vimentin.Conclusion： Teratomas were common in mediastina,but the tumors mainly contained hepatic tissue were very rare.

关 键 词：纵膈 肝 畸胎瘤 临床病理 免疫组化 

分 类 号：R730.269[医药卫生—肿瘤]