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作 者:陈小刚[1] 张青汉[1] 叶绪龙[1] 王瑜[1]
机构地区:[1]武汉大学医学院附属黄石中心医院泌尿外科,湖北黄石435000
出 处:《临床泌尿外科杂志》2010年第8期591-592,594,共3页Journal of Clinical Urology
摘 要:目的:分析肠膀胱肿瘤的发病原因和诊治。方法:报告1例膀胱癌根治、直肠代膀胱、结肠造口术后8年肠膀胱发生绒毛状腺瘤伴高级别上皮瘤样变的临床资料,并复习相关文献予以讨论。结果:肠膀胱肿瘤多发生在肠膀胱术后10年,临床表现常为肉眼血尿,肿瘤多生长在输尿管-肠吻合缘,良性肿瘤行肿瘤电切术,预后良好。结论:肠膀胱肿瘤的发展过程中,肠膀胱经历了形态学和分子学的改变,较早诊断可获得较好的疗效,对肠膀胱术后的患者临床上应严密随访。Objective:To explore the etiology and the strategy for diagnosis and treatment of bowel neobladder tumor. Methods:We report the case of viilous adenoma with high-grade dysplasia in the rectal segment after radical cystectomy and rectal bladder with permanent abaominal sigmoidostomy. The pertinent literature has been reviewed. Results:A long latency period for the development of neoplastic change was 10 years after intestinal neobladder, patients usually presented with gross hematuria. Adenocarcinoma or adenomas arose from the ureterocol- ic anastomosis, the complete transurethral resection of the adenomas was considered adequate conservative man- agement. Conclusions:an intestinal neobladder may undergo all the morphologic and molecular changes observed in the development of intestinal adenocarcinoma. Hence, emphasizing the importance of careful lifelong follow up, including cystoscopy and urine cytology, of all patients who undergo urinary tract reconstruction with intestinal segments.
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