胃癌手术患者预后的多因素分析  

Multivariate prognostic factors analysis of patients with gastric cancer undergoing operation

作　　者：欧阳洋[1] 欧阳植庭[1] 夏绪东[1] 

机构地区：[1]中南大学湘雅医院普通外科,湖南长沙410008

出　　处：《中国普通外科杂志》2010年第10期1061-1064,共4页China Journal of General Surgery

摘　　要：目的探讨影响胃癌手术患者预后的相关因素。方法应用单因素和多因素的分析方法,回顾性分析1990年1月至2001年12月有完整临床资料和随访资料的887例胃癌患者的临床资料。结果胃癌患者总的1年生存率为79.63%,3年生存率为49.29%,5年生存率为43.40%。单因素分析结果显示肿瘤部位,TNM分期,病理分型,手术方式,化疗方法与患者的预后具有相关性。应用COX回归模型分析显示TNM分期,病理分型,手术方式,化疗方法是影响胃癌患者手术预后的相关因素。结论 TNM分期,病理分型,手术方式,化疗方法是影响胃癌手术患者预后的重要指标。Objective To analyze the related factors affecting the prognosis of gastric cancer patients undergoing operation.Methods The clinical characteristics and follow up data of 887 patients with gastric cancer treated from January 1990 to December 2001 in our hospital were retrospectively analyzed by univariate and multivariate methods.Results Of the 887 cases,the overall 1-,3-and 5-year survival rate was 79.63%,49.29% and 43.40%,respectively.In the univariate analysis,tumor location,TNM stage,pathological type,operative method,and chemotherapy were related to the prognosis of patients with gastric cancer.Multivariate Cox model analysis showed that TNM stage,pathological type,operative method,and chemotherapy were the related factors for patients with gastric cancer.Conclusions TNM stage,pathological type,operative method,and chemotherapy are important prognostic factors for patieuts with gastric cancer undergoing operation.

关 键 词：胃癌 预后 多因素分析 

分 类 号：R735.2[医药卫生—肿瘤]