CT引导射频消融术治疗非小细胞肺癌35例  

CT-guided radiofrequency ablation in treatment of 35 cases of non-small cell lung cancer

作　　者：张开贤[1] 李苓[1] 邢超[1] 张开国[1] 袁倩倩[1] 郝崇礼[1] 满其荣[1] 王伟[1] 杨森[1] 滕颖[1] 

机构地区：[1]山东滕州市中心人民医院肿瘤科,山东滕州277500

出　　处：《中华肿瘤防治杂志》2010年第18期1484-1486,共3页Chinese Journal of Cancer Prevention and Treatment

摘　　要：为了探讨CT引导下射频消融术(RFA)治疗非小细胞肺癌(NSCLC)的疗效及安全性,对35例NSCLC进行了CT引导下RFA治疗,其中鳞癌12例,腺癌20例,鳞腺癌1例,大细胞癌2例;中央型肺癌4例,周围型肺癌31例。肿瘤直径≤3cm6例,3～5cm21例,>5cm8例。射频消融过程中多数病灶阴影增大,边缘模糊,部分病灶出现蜂窝气泡样改变,术后3个月复查CT显示28个病灶缩小,总有效率(CR+PR)为80.0%。术后出现少量咯血5例,气胸5例,轻度发热7例。初步研究结果提示,CT引导RFA术治疗NSCLC是一项安全有效的微创技术,值得推广应用。The objective of this study was to access the security and therapeutic value of CT-guided radiofrequency ablation （RFA） in the treatment of non-small cell lung cancer （NSCLC）.Thirty-five patients with NSCLC were treated with CT guided RFA,which including 4 cases of central lung cancer and 31 cases of peripheral lung cancer,as well as in different pathology types and tumour size （12 SC,20 adenocarcinoma,1 mixed carcinoma and 2 large cell carcinoma）.Tumor diameter：≤3 cm 6 cases,3-5 cm 21 cases,5 cm 8 cases.During the process of RFA,the volume of lesions in the majority cases became lager,also with a fuzzy edge.Some lesions showed bubble-like changes.Three months later,CT showed that 28 lesions reduced,the total effective rate （CR ＋ PR） was 80.0%.There was a little amount of hemoptysis in 5 cases,pneumothorax in 5 cases,and 7 cases of mild fever.In conclusion,CT guided RFA is a safe,effective and minimal invasive therapeutic method for NSCLC.

关 键 词：癌 非小细胞肺 肺肿瘤/放射疗法 射频消融术 

分 类 号：R734.2[医药卫生—肿瘤]