皮肤镜诊断面部光线性角化病的初步研究  

A preliminary evaluation of dermoscopy in the diagnosis of facial actinic keratosis

作　　者：顾锐龙[1] 陈晓栋[1] 顾黎雄[1] 

机构地区：[1]南通大学附属医院皮肤性病科, 江苏南通226001

出　　处：《中华皮肤科杂志》2010年第11期770-772,共3页Chinese Journal of Dermatology

摘　　要：目的 评价皮肤镜在面部光线性角化病诊断中的价值.方法 面部疑似光线性角化病患者40例,其中男27例,女13例;年龄46～88岁;病程2～20年.分别对其行皮肤镜检查及组织病理学检查;以病理诊断为＂金标准＂,通过诊断性试验的研究方法,研究皮肤镜诊断面部非色素性光线性角化病的敏感性、特异性及一致性.结果 与病理诊断比较,两位医生皮肤镜诊断面部非色素性光线性角化病的灵敏度、特异度、Youden指数及Kappa值分别为90.91%、88.89%、79.80%、0.798（χ2=0.25,P〉0.05）和86.36%、94.44%、80.80%、0.800（χ2=0.25,P〉0.05）.结论 皮肤镜检查对面部非色素性光线性角化病诊断与病理组织检查结果存在较好的一致性.Objective To evaluate the diagnostic ability of dermoscopy in facial actinic keratosis.Methods Forty patients with facial lesions suspected for actinic keratosis were enrolled from April 2009 to November 2009. There were 27 males and 13 females among these patients aged from 46 to 88 years. The disease course varied from 2 to 20 years. Lesional specimens were obtained from the subjects and underwent dermatoscopic and histopathologic examinations. The sensitivity, specificity and consistency with pathology were calculated for dermoscopy in the diagnosis of nonpigmented facial actinic keratosis. Results The sensitivity, specificity, Youden index and Kappa index of dermoscopy were 90.91%, 88.89%, 79.80% and 0.798（χ2 = 0.25, P 〉0.05） respectively in the diagnosis of facial nonpigmented actinic keratosis made by one dermatologist,86.36%, 94.44%, 80.80% and 0.800 （χ2 = 0.25, P 〉 0.05） respectively in that made by another dermatologist.Conclusion There is a high consistency between dermoscopy and histopathology in the diagnosis of facial nonpigmented actinic keratosis.

关 键 词：光线性角化病 皮肤镜检查 诊断 

分 类 号：R739.5[医药卫生—肿瘤]