肿瘤热疗用CNTs/Fe3O4热种子复合材料的制备及表征  

Preparation and characterization of CNTs/Fe_3O_4 thermo-seed composite for tumor hyperthermia

作　　者：刘爱红[1] 孙康宁[2] 李爱民[2] 

机构地区：[1]黄石理工学院化学与材料工程学院,黄石435003 [2]山东大学液态结构及其遗传性教育部重点实验室,山东省工程陶瓷重点实验室,济南250061

出　　处：《化工新型材料》2010年第11期43-45,共3页New Chemical Materials

基　　金：国家自然科学基金项目(50672051);黄石理工学院科研项目(09yjz01R)

摘　　要：采用化学共沉淀结合水热处理的方法,控制一定的反应条件,制备了微波肿瘤靶向热治疗用碳纳米管/四氧化三铁(CNTs/Fe3O4)热种子材料,并对所得的复合材料进行了相应的检测。实验结果表明:Fe3O4纳米小粒子在CNTs的表面包覆均匀,具有普遍性CNTs/Fe3O4复合材料具有纯Fe3O4相似的超顺磁性,当CNTs的质量分数为10%时,其比饱和磁化强度为64.53emu/g,矫顽力为14.03Oe,可以实现CNTs在磁场中的定向;CNTs/Fe3O4复合材料在0～5GHz范围内具有较好的吸波性能,当CNTs的质量分数为4%时,CNTs/Fe3O4复合材料的吸收峰在2.2GHz附近,反射率达-19dB,频宽为1G左右。因此,CNTs/Fe3O4复合材料有望作为热种子材料用于肿瘤热疗。The CNTs/ Fe3O4 thermo-seed material was prepared by a simple and effective coprecipitation and hydrothermal treatment method.The results showed that Fe3O4 nanoparticles were decorated on CNTs successfully;Fe3O4 nanoparticles in the surface of carbon nanotubes were uniform and universal;The hysteresis loops of the decorated MWNTs were measured by vibrating sample magnetometer（VSM）,and the results showed that the composite was ferromagnetism with the saturated magnetization of 64.53 emu/g,and the coercive of 14.03 Oe.CNTs/Fe3O4 composite also had better absorbing properties in the 0～5 GHz range.when CNTs content was 4%,the reflection loss value of-19dB and the bandwidth of 1G had been obtained at 2.2GHz.The results indicated that this composite had significant potential for electromagnetic wave absorption application in tumor hyperthermia.

关 键 词：碳纳米管 四氧化三铁 肿瘤热疗 吸波性能 

分 类 号：R318.08[医药卫生—生物医学工程]